In the era of digital economy, new formats and scenarios continue to emerge. A group of science and technology innovation enterprises, manufacturing enterprises, and specialized, refined, and new small and medium-sized enterprises are developing and growing, and the size of the maker group is also expanding day by day. Cultivating and promoting the entrepreneurial spirit is of great significance in guiding and promoting the healthy development of the private economy, enhancing market and social vitality. The entrepreneurial spirit embodies the spirit of exploration, inspiring enterprises to tackle research and development challenges, dare to take risks, and promote disruptive technological innovation. With the increasing progress of economic development and social change, various industries are constantly exploring the forefront of technology. It is necessary for relevant enterprises to increase their efforts in scientific and technological innovation, and entrepreneurs need to unleash their innovative spirit. Enterprises are the main body of innovation, and the research and industrialization of major technologies such as chips, 5G, generative artificial intelligence, and biomedicine cannot be separated from the innovative leadership of a group of outstanding entrepreneurs. According to the global trend of a new round of industrial revolution, the digital economy is an important field where cutting-edge technologies are concentrated and emerging. Its innovation process is largely focused on collecting and processing data, utilizing algorithms, and artificial intelligence. Chinese enterprises are actively exploring this area. The entrepreneurial spirit also reflects the spirit of exploration, helping to explore potential business opportunities and promoting innovation in technology application scenarios. The rapid transformation of technology is driving the accelerated evolution of economic forms and industrial organizational patterns. At present, the information industry has brought revolutionary changes to economic and social activities, promoting high-quality development of related industries such as healthcare and environmental protection. The transformation of industries from ideals to reality, from technological research and development to industrial development, and from small-scale pilot projects to benefiting society requires entrepreneurs to continuously exert their spirit of exploration, actively utilize the power of enterprises, and push emerging technologies to the vast market. This process will promote high-quality economic development and better meet the needs of the people for a better life. The entrepreneurial spirit also embodies the pioneering spirit, which helps to grasp the forefront trends of industrial development and promote innovation in the industrial chain. Excellent entrepreneurs are not imitators and followers, but innovators who excel at making disruptive innovations in technology and application scenarios. Manifested in the industrial chain, it is the pursuit of breakthroughs in high-precision and cutting-edge links, thereby leading the development of the industry. The higher the knowledge intensity, the stronger the specificity of human capital, the more intermediate links in the industrial chain, and the higher the technological content in cutting-edge fields, the more reliant entrepreneurs are on showcasing their pioneering spirit. Many outstanding entrepreneurs in our country are committed to research and investment layout in cutting-edge fields such as digitalization, greening, and new industrialization, demonstrating their responsibilities and responsibilities. At present, with the updating of knowledge, the evolving trends of industries, and the complex and ever-changing international economic environment, entrepreneurs need to identify effective information more accurately, make strategic judgments on the development prospects of industries in a timely and sensitive manner, and lead the rapid development of strategic emerging industries. The recently held Central Economic Work Conference emphasized that scientific and technological innovation should lead the construction of a modern industrial system. We should promote industrial innovation through technological innovation, especially by using disruptive and cutting-edge technologies to give birth to new industries, models, and driving forces, and develop new quality productive forces. The stability of economic policies helps to enhance entrepreneurs' confidence in long-term economic growth. A series of encouragement and support policies help to create a favorable environment for enterprises in the whole society