Author: Yu Hejun (Deputy Director of the Elected Office of the Work Bureau of the Academic Department of the Chinese Academy of Sciences) pointed out in the report of the 20th National Congress of the Communist Party of China that the great rejuvenation of the Chinese nation should be comprehensively promoted with Chinese path to modernization. The report also profoundly elaborated the important characteristics of Chinese path to modernization. Chinese path to modernization is a modernization with a huge population, a modernization that all people are prosperous together, a modernization that coordinates material civilization and spiritual civilization, a modernization that people and nature coexist in harmony, and a modernization that takes the path of peaceful development. From the perspective of science and technology, science and technology modernization is an important component of Chinese path to modernization, and science and technology is also the key word that all features of Chinese path to modernization point to. Only through scientific and technological innovation can we make the cake of social wealth bigger in the development of the country itself, achieve the common prosperity and high level of material civilization of all the people, including more than one billion people, achieve green development, low-carbon development and sustainable development in the relationship between people and nature, achieve "freedom of all kinds of frost", and ensure national security with scientific and technological strength in the relationship between people and the world, Make China an important force in maintaining world peace. Only by popularizing science, improving the scientific quality of the whole people, and promoting the integration of advanced culture and the construction of spiritual civilization can the material civilization and spiritual civilization complement each other, which is the ideological and cultural value of science and technology. As a major event with far-reaching influence in human history and a new form of human civilization, Chinese path to modernization not only has the common characteristics of modernization in all countries, but also has Chinese characteristics based on its own national conditions. There is no precedent to follow, no operation to copy, and the way forward will not be smooth. Theory guides practice, and thought is the guide of action. Therefore, strengthening scientific and technological strategic consultation proposed in the report of the 20th National Congress of the Communist Party of China is also the proper meaning of Chinese path to modernization. As a think tank, China's science and technology think tanks should focus on the development and security issues in the process of Chinese path to modernization, play the role of strategic scientists, look ahead to the development trend of science and technology, go deep into theory and practice, really study problems, research real problems, and put forward more original and profound ideas that meet the national conditions, more professional, constructive, and practical opinions and suggestions, We should deal with the future risks, challenges and uncertainties with scientific logic and certainty, and provide solutions for China's big ships to go steady and far in the "high winds and rough waves". At the same time, the realization of national strategies and goals needs to be supported at the regional level. The report of the 20th National Congress of the Communist Party of China pointed out that "promote coordinated regional development. Deeply implement the strategy of coordinated regional development, major regional strategy, main functional area strategy, and new urbanization strategy, optimize the layout of major productive forces, and build a regional economic layout and territorial space system with complementary advantages and high-quality development." China is a vast country with different development modes and paths. If the economic volume is calculated separately, based on the 2021 economic data, Guangdong, Zhejiang, Jiangsu, Shandong and Henan are all the top 20 economies in the world, about the size of a medium-sized European country. For example, Guangdong's GDP has surpassed Russia, Canada and South Korea, and is the top ten economies in the world. Zhejiang has surpassed the Netherlands, and Henan has surpassed Switzerland. If the economic and social development experience, lessons and stories of relevant countries are worth their wisdom