Scientific Liver Protection Refuses

2023-04-07

The liver is known as the "life tower" of the human body, carrying various "heavy responsibilities" such as secretion, metabolism, detoxification, coagulation, etc. every day. It is closely related to other organs in the body, and its importance is self-evident. How to nourish and protect the liver and stay away from liver diseases in daily life? What should we do if liver disease is detected and even progresses to cirrhosis or liver cancer? Recently, at the Love Liver Day Science Popularization Lecture held in the Datansha Campus of the First Affiliated Hospital of Guangzhou Medical University (hereinafter referred to as "Guangzhou Medical First Hospital"), a renowned Nanshan medical team composed of multi-disciplinary experts from the hospital advised citizens from multiple perspectives on how to deal with hematemesis, black stools, and ascites in liver cirrhosis. Many liver cirrhosis patients progress to the late stage and suffer from hematemesis, black stools, and ascites, causing unbearable pain, and even pessimistic belief that they cannot be saved, Is that really the case? Professor Xiong Bin, the director of the Interventional Department of the First Hospital of Guangzhou Medical University, suggested that decompensated liver cirrhosis patients with complications such as acute bleeding from esophageal varices should not be pessimistic. In clinical practice, endoscopic treatment+non-selective treatment can be chosen β Receptor blockers to help stop bleeding. If the above methods still fail to stop bleeding, the interventional department also has a "powerful hemostatic tool" - transjugular intrahepatic portosystemic shunt (TIPS). In the past, traditional large incision surgery was often used for the surgical treatment of patients with liver cirrhosis and portal hypertension, which resulted in significant trauma and slow patient recovery. With the development of minimally invasive interventional therapy technology, TIPS has emerged. This new interventional therapy for the treatment of portal hypertension and upper gastrointestinal bleeding has been widely applied to esophageal and gastric variceal bleeding caused by cirrhosis and portal hypertension, stubborn pleural and ascites, as well as Budd Chiari syndrome, hepatic sinus syndrome, portal hypertension combined with portal thrombosis, etc. When implementing this minimally invasive intervention procedure, the patient only needs to receive local anesthesia, then open a small opening in the neck, and use instruments such as a guide wire and catheter to establish a personal flow channel between the hepatic vein and portal vein using a stent, which quickly reduces the pressure gradient of the hepatic vein and has a significant hemostatic effect. For patients with acute bleeding from gastric varices, endoscopic treatment is usually not ideal and is prone to rebleeding. Xiong Bin suggests that direct TIPS treatment can be considered. Early prevention and early diagnosis and treatment of liver cancer are not afraid of the hidden onset of liver cancer. Early symptoms are often not obvious, which is why many patients are already in the middle and late stages of initial diagnosis, and the treatment effect is not ideal. How to reverse this unfavorable situation? "As long as early prevention, early treatment and comprehensive treatment are achieved, the 5-year survival rate of liver cancer can be significantly improved." Professor Wang Guoying, director of the Department of Hepatobiliary Surgery of the First Hospital of Guangzhou Medical College, analyzed that most of China's liver cancer occurs on the basis of hepatitis B, and the trilogy of hepatitis B, cirrhosis and liver cancer is the most common pathogenesis, but hepatitis C, alcoholic hepatitis, long-term consumption of moldy food, etc. are also pathogenic factors of liver cancer. He suggested that people with hepatitis B or hepatitis C virus infection, long-term alcoholism, nonalcoholic steatohepatitis, eating food contaminated with aflatoxin, cirrhosis caused by various reasons, and people with a family history of liver cancer, especially men over 40 years old, should have their serum alpha fetoprotein and liver ultrasound checked at least once every six months. For patients with abnormal liver ultrasound and alpha fetoprotein, enhanced CT, magnetic resonance imaging, contrast-enhanced ultrasound, etc. can be used to further clarify the diagnosis.

Edit:Niexiaoqian    Responsible editor:Guanguan

Source:GMW.cn

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