"In the future, can computers run on human brain cells?" This question seems to be "the brain hole is wide open", but researchers from Johns Hopkins University in the United States are groping for the answer, and recently announced the relevant plan. They believe that Organ-like Intelligence (OI) has practical application prospects, and is even more powerful than AI. However, this research is still in its infancy, and it is expected that it will take decades to enter the stage of animal testing. In addition, it also needs to address ethical challenges. ChatGPT, a brain-like structure with a large pen tip, has made people realize that machines can perform intelligent behaviors similar to human beings. In some fields, machines have even surpassed humans. For example, in 2016, the computer program AlphaGo defeated the world champion of Go, Li Shishi. But it is undeniable that in many fields, AI is still far from human intelligence. For example, humans can instantly distinguish cats and dogs, but machines can't. Some websites use "Turing test" to verify whether the user is human or machine. In terms of emotional cognition, the human brain has incomparable ability, which is related to the large number of neurons formed during the evolution of the brain. Therefore, whether to replicate this ability has become a topic of concern for researchers. This includes Professor Thomas Harton of Johns Hopkins University in the United States. He believes that computing and artificial intelligence have been driving the technological revolution, but they are also reaching the limit. Biocomputing has great potential in improving efficiency. Hartong and his colleagues conceived that with brain-like organs as "hardware", it is expected to develop a "biological computer". They recently published this research plan in the journal Frontier of Science, involving bioengineering and machine learning. The so-called "organ like" is a kind of tissue that is cultivated in the laboratory and has similar function to a certain organ, usually derived from stem cells. For many years, scientists have experimented with this as a substitute for kidneys, lungs and other organs to avoid harm to humans or animals. "Brain like organ" refers to a cell culture of the size of a pen tip, in which there are neurons with organ like function. The reason why we can extract this kind of cell is due to a pioneering research result of stem cell research pioneer John Gordon and Yamanaka Nobumi - the ability to extract cells from fully developed tissues such as skin. On this basis, Hartong defined "brain-like intelligence" as "reproduction of cognitive functions, such as learning and sensory processing, in human brain models cultivated in the laboratory". "Brain-like intelligence" is also known as "intelligence in experimental vessels". One problem that needs to be solved in this study is how to communicate with "brain like organs" in order to send information to them and receive the reading they are "thinking". "We have developed a brain-computer interface device," Harton said, which is equivalent to using this device densely covered with tiny electrodes to depict EEG for "brain-like organs". Organ intelligence technology with multiple meanings seems to have made progress. In October last year, Brett Kagan, chief scientific officer of the Brain Cortex Laboratory in Melbourne, Australia, and others released research results that brain cells in petri dishes can "play" with a model called“