Recently, some antiviral drugs used to treat COVID-19 infection have been dubbed as "special drugs", causing many netizens to pay attention and rush to buy them. Is it necessary to hoard these antiviral drugs? How to use it scientifically and rationally? The National Health Commission organized Tong Chaohui, Vice President of Beijing Chaoyang Hospital affiliated to Capital Medical University and Director of Beijing Institute of Respiratory Diseases, and Wang Guiqiang, Director of Infection Department of Peking University First Hospital, to respond. "First of all, it should be clear that there is no specific drug for COVID-19 at present. Some antiviral drugs can inhibit and interfere with the replication of COVID-19, but these drugs need to be used in the early stage of infection, and should be standardized under the guidance of doctors." Tong Zhaohui said. Tong Chaohui introduced that antiviral drugs had better effect when used within 5 days, especially within 48 hours. When the virus has just entered the human body and has not been replicated in large quantities, antiviral drugs can reduce the viral load, reduce the virus's attack on the human immune system, and then reduce the disease to severe and critical diseases through their own resistance. If the onset time is too long and the disease has progressed to severe and critical disease, antiviral drugs are ineffective. "At the same time, these antiviral drugs are conditionally recommended for specific populations. For light, ordinary high-risk groups with severe and dangerous development, such as the elderly with basic diseases, they can effectively reduce the severity rate, but it is useless to use them in young people and other groups without high-risk factors." Tong Zhaohui said. Experts remind that there are many precautions in the use of antiviral drugs. Adverse reactions may occur, and interactions with other drugs may also occur. The use must be standardized under the guidance of doctors. It is not recommended that the public hoard drugs and use them at home. "For example, some patients with severe liver and kidney function damage may need to adjust the dosage of antiviral drugs or even not use these drugs; if you are using some statins, you cannot use such drugs as Nematvir at the same time. If patients blindly use drugs at home, there is a safety risk." Wang Guiqiang said. Wang Guiqiang said that comprehensive treatment and early intervention were emphasized for COVID-19 infection. It is suggested that early close monitoring and follow-up should be carried out for people at high risk of severe diseases, especially the elderly with underlying diseases who are lying in bed. "When symptoms such as dyspnea, wheezing or low blood oxygen saturation occur, you should go to the hospital or community health service institution to see a doctor in time. Early treatment includes antiviral drugs and oxygen therapy. Now Beijing, Shanghai and other cities have carried out oxygen therapy services at the community level." Tong Zhaohui also reminded that medical personnel and professionals must strengthen the training on the use of new antiviral drugs to fully understand their mechanism of action, indications Adverse reactions and interactions with other drugs reduce the risk of drug clinical use. Recently, intravenous gamma globulin, another therapeutic drug recommended in the ninth edition of the diagnosis and treatment plan, has also attracted many netizens to buy. In this regard, Wang Guiqiang introduced that intravenous gamma globulin can reduce inflammatory reaction, but it is only recommended to use in the treatment of severe patients. "It is basically necessary for patients entering the ICU to use it, and it can only be effective in certain situations such as inflammatory factor storms. It is not suitable to use it at home, nor can it prevent COVID-19 infection