Recently, the crew of Shenzhou XIV astronauts successfully opened the "home gate" and warmly welcomed the crew of Shenzhou 15 to enter the "Tiangong". The first "space rendezvous" between the two astronaut teams marked a new stage in China's space science and technology development, which also reflected the important role of national strategic science and technology forces. Aerospace science and technology is an important field of scientific and technological progress and innovation, which can not be separated from the strong national laboratory system as a support. The national laboratory is a strategic scientific and technological force that reflects the national will, realizes the national mission and represents the national level, and is a strong support for achieving self-reliance and self-improvement in high-level science and technology. The establishment of a group of national laboratories with larger scale, interdisciplinary integration and comprehensive integration can comprehensively improve the overall effectiveness of the national innovation system and form new advantages in international competition. As a large comprehensive research base, the National Laboratory is the core support for high-quality development and high-level security. To win the battle against key core technologies, we need to give full play to the advantages of our socialist system in focusing our efforts on major issues, optimize the allocation of superior resources, and establish a number of national laboratories, so that the "great powers and heavy weapons" can become the "sea calming needle" to maintain the overall national security. However, the construction of the national laboratory still needs to further strengthen the top-level design and system planning, clarify the positioning, goals and tasks, and establish a new mode of modern management and operation. The construction of national laboratory system should highlight mission driven and task oriented. Focusing on the national strategic needs, tackling key core technologies in basic and strategic fields, producing more strategic and key scientific and technological achievements, and systematically supporting the construction of a modern and powerful country are the mission of the national laboratory system construction. National laboratories should face the world's scientific and technological frontier, strengthen original innovation, and strive to achieve more breakthroughs from 0 to 1. We should face the main battlefield of the economy and promote the deep integration of scientific and technological innovation and industrial development, especially the development of the real economy. To meet the major national needs, we need to solve the "choke" problem in key core technology areas. We should face the people's life and health, substantially increase the supply of public science and technology, and constantly meet the people's growing needs for a better life. The construction of national laboratory system must adhere to the concept of system. The national laboratory system is not a simple superposition of existing institutions or bases, but a multi-level, multi type, multi field cross integration and complementary advantages. Only systematic layout and promotion can form a strong joint force to promote independent innovation. We should strengthen forward-looking thinking and plan the direction of national laboratory system construction from the urgent needs and long-term needs of the country. We should strengthen the overall planning, take into account the relationship between independence and openness, current and long-term, local and overall, promote the comprehensive integration of different types of innovation subjects, and focus on superior forces to carry out collaborative research. We should strengthen the overall promotion, establish and improve the laboratory system led by the national laboratory and supported by the national key laboratory, and