Recently, the General Office of the CPC Central Committee and the General Office of the State Council issued the Opinions on Strengthening the Construction of High skilled Talents in the New Era (hereinafter referred to as the Opinions). The Opinions put forward that skilled personnel are an important force to support Made in China and Created in China. At present, we are in a period of strategic opportunities for the great rejuvenation of the Chinese nation, as well as an excellent period for all kinds of talents to make contributions and make great achievements. Innovation is the first driving force to lead development. Skilled personnel are the first array of talents and innovation leaders. They need to play a good role in leading the country's strength and national rejuvenation in the critical period. In terms of self construction of scientific research talents, attention should be paid to adhering to the five orientations. Adhere to the correct political orientation. Political orientation is a matter of direction, and the slightest difference is a thousand miles away. The leadership of the Party is the greatest advantage of the socialist system with Chinese characteristics, and an important guarantee for the healthy growth of skilled personnel and their better functioning; The key to running China's affairs well lies in the Party. Therefore, we must adhere to the Party's overall leadership in building a team of highly skilled talents to ensure the correct political direction. Adhere to the people-centered orientation. The people's character is the most distinctive political character of Marxism. In the Communist Manifesto, Marx and Engels pointed out that the proletarian movement is an independent movement for the vast majority of people and for their benefit. It can be seen that people's yearning for a better life is also the goal of highly skilled talents. Skilled personnel should always regard the people's yearning for a better life as the highest goal in life, and regard the people as the center as the foothold and starting point for adhering to the correct political orientation. Adhere to the realistic demand orientation. Adhering to the realistic demand orientation is an effective way to implement the people centered orientation. Realistic needs are the examination questions given by the times and the real needs of the people. Adhering to the people as the center, we must pay attention to the problems of the times and the real needs of the people, especially the major practical problems that affect the production and life of the people. The more important the practical problems are, the more skilled people need to invest more energy and time to study and solve them. Adhere to the guidance of big science. Adhere to the problem oriented, objective needs to adhere to the big science oriented, and lay a solid foundation of knowledge tools for solving problems. The so-called big science orientation means that we should look at problems, study problems and solve problems from a multidisciplinary perspective. In terms of general methodology, we should adhere to dialectical materialism. Philosophy provides methodology for technological innovation and progress at a higher level; The scientific nature of dialectical materialism methodology has withstood the test of all human cognitive history, providing a scientific way of thinking for knowledge renewal and technological innovation. Therefore, skilled talents should always adhere to innovation and development under the guidance of dialectical materialism philosophy, fully integrate the theoretical perspective of natural science and social science in the study of specific issues, and integrate theoretical learning with technology