According to the needs of epidemic prevention and control, the comprehensive group of the joint prevention and control mechanism of the State Council decided to promote the monitoring mode of "antigen screening and nucleic acid diagnosis", and add antigen detection as a supplement on the basis of nucleic acid detection. Recently, the mechanism synthesis group has formulated and issued the "COVID-19 antigen detection application plan (Trial Implementation)", requiring all localities to conscientiously organize and implement it. Up to now, five self-test products of neocoronavirus antigen have been approved for listing in China, including Nanjing nuovizan, Beijing jinwofu, Shenzhen Huada Yinyuan, Guangzhou Wanfu biology and Beijing huaketai biology. Epidemic prevention and control, such as fighting water and fire, should always race against the epidemic, race against time, race against every minute and take one step first. According to the transmission characteristics of Omicron, the first batch of rapid test products of coronavirus antigen were put on the market. People in home isolation observation, close contact and secondary close contact, entry isolation observation, sealing and control areas can carry out antigen detection once a day without leaving home. On the basis of nucleic acid detection, adding antigen detection as a supplement, formed a strong combination of nucleic acid detection, antigen detection and antibody detection "three swordsmen", and further optimized the COVID-19 detection strategy. Compared with nucleic acid detection, antigen detection is faster and easier to operate. Some reagents can produce results in 15 minutes. People can buy detection by themselves, which is conducive to early detection, improve the sensitivity of monitoring and early warning, and make the monitoring mode of "antigen screening and nucleic acid diagnosis" more efficient and accurate. However, it should be noted that antigen detection is only a supplementary means and cannot completely replace nucleic acid detection. Because there is no amplification process, the sensitivity of antigen detection still can not keep up, especially when the infection time is long and the virus load becomes low, it is easy to increase the risk of "false negative" and even miss detection. The National Health Council stressed that nucleic acid testing is still the basis for the diagnosis of COVID-19 infection. Scientific epidemic prevention is always the hard truth and the hardest core of epidemic prevention. Since the outbreak, from decoding the virus to vaccine research and development, from identifying the source of infection to cutting off the route of transmission, from health code monitoring to "standing firm" the commanding height of epidemic prevention, to the listing of self-test products of neocoronavirus antigen and adding new "weapons" of epidemic prevention, relying on scientific attitudes and methods, we have a magic weapon to protect our health. No weapon can beat the world. Relying on science and technology to overcome the epidemic requires not only scientific and effective management, but also the trust and application of science and technology in the whole society. We should make good use of the scientific detection strategy of the "three swordsmen", firmly grasp the initiative to compete with the virus, and protect people's lives and health. (Xinhua News Agency)