As the main force of basic research and the new force of major scientific and technological breakthroughs, high-level research universities must consciously fulfill the mission of high-level scientific and technological self-reliance and self-improvement, and better integrate the development of science and technology as the first productive force, the cultivation of talents as the first resource, and the enhancement of innovation as the first driving force. Only by further strengthening organized scientific research, organizing major tasks closely around the country's major needs, Relying on the large platform to form a large team, universities, especially high-level research universities, can continuously achieve new achievements in scientific and technological research. The number of patent authorizations will increase from 69000 in 2012 to 308000 in 2021, with an increase of 346.4%; The annual patent conversion amount increased from 820 million yuan to 8.89 billion yuan, an increase of nearly 10 times... The data released by the Ministry of education a few days ago shows that since the 18th National Congress of the Communist Party of China, the comprehensive strength of scientific and technological innovation of China's colleges and universities has made a great leap. The Ministry of education has organized colleges and universities to build more than 2000 major scientific research platforms of various types, and initially formed a scientific research platform system with clear levels, reasonable layout and effective support. It is an innovative country and an educational power It has made important contributions to building a strong country through science and technology. Today's world is experiencing great changes that have not been seen in a century. Scientific and technological innovation is one of the key variables. It also made important instructions such as "accelerating the construction of an innovation consortium led by leading enterprises, supported by universities and institutes, and coordinated by various innovation subjects", "forming a new mode of teaching and research and collaborative education, laying a solid foundation for science and technology innovation in China" and "striving to build a discipline system, academic system and discourse system with Chinese characteristics, Chinese style and Chinese style". As the main force of basic research and the new force of major scientific and technological breakthroughs, high-level research universities must consciously fulfill the mission of high-level scientific and technological self-reliance and self-improvement, and better integrate the development of science and technology as the first productive force, the cultivation of talents as the first resource, and the enhancement of innovation as the first driving force. Looking back on the development process of the past 10 years, the scientific and technological innovation of colleges and universities has shown more prominent characteristics such as "national mission", more prominent "active service" and more prominent "quality improvement". Pay attention to the national demand and solve more "bottleneck" problems; Pay attention to condensing scientific issues from the actual needs of the industry and accelerate the deep integration of industry, University and research; We will pay attention to promoting the reform of scientific and technological evaluation and the transformation of achievements, so as to realize the transformation from extensional expansion to connotative high-quality development. Many high-level research universities adhere to independent innovation and leading edge, adhere to the integration of science and education, scientific research and education, adhere to people-oriented, deepen reform, liberate and stimulate the scientific and technological innovation potential of scientific research personnel, and promote the transformation of major original innovation and key core technology breakthroughs into advanced production capacity. It is not difficult to understand why, in the past 10 years, Chinese universities have made one major scientific research achievement after another in many fields, such as quantum communication, prevention and treatment of COVID-19, spacecraft material technology, sky and earth remote sensing. Now, more than ever before, China's economic and social development and improvement of people's livelihood need scientific and technological solutions, and we need to strengthen innovation as the first driving force. Facing the future, colleges and universities as a national strategic scientific and technological force