As the United Nations diabetes Day approaches, Peng Yongde, chief physician of the endocrinology department of Shanghai First People's Hospital, told reporters on the 12th that if diabetes patients are infected with herpes zoster, their blood sugar control will become more difficult. Compared to healthy individuals, they are more likely to experience postherpetic neuralgia and experience more intense pain. Can people with chronic diseases, including diabetes patients, be vaccinated? Peng Yongde explained: "Chronic diseases, including diabetes, are not absolute taboos for vaccination, but need to scientifically grasp the timing of vaccination. For middle-aged and elderly people with basic diseases, if they are in an acute attack or disease progression period, the vaccination needs to be postponed; in addition, some middle-aged and elderly people are also advised to slow down vaccination when they have an acute disease and serious symptoms." Herpes zoster, commonly known as "loincloth dragon" and "snake loincloth", is an infectious skin disease caused by reactivation of varicella zoster virus. More than 90% of adults have the virus lurking in their bodies. As age increases and immune function declines, the virus may reactivate and trigger shingles. About one-third of people will develop shingles in their lifetime. In addition to causing skin lesions to patients, the main symptom of herpes zoster is pain, and postherpetic neuralgia is the most common complication. Some patients may also cause serious complications in the eyes, even blindness. This expert suggests that middle-aged and elderly people should be vaccinated to prevent shingles. He pointed out that shingles is not a disease that will be immune for life after one infection, and there is a possibility of recurrence. For middle-aged and elderly patients with comorbidities, the physical and psychological burden they need to bear will be greater, and it will also affect the quality of their family life. On the same day, at the media exchange meeting with the theme of "scientific and comprehensive management, safeguarding the health of diabetes patients", the reporter learned that with the growing aging problem of China's population, the prevalence of diabetes among the middle-aged and elderly groups has significantly increased. Diabetes patients may have a variety of skin lesions. Research shows that the risk of herpes zoster in patients with diabetes is 1.26 times that in people without diabetes, and the risk of post herpetic neuralgia is higher. After diabetes patients suffer from herpes zoster, blood sugar control may be affected, resulting in increased difficulty in diabetes management. It is very important to pay attention to the multi disease co management of diabetes population and stay away from herpes zoster to improve the quality of life of patients. What should be paid attention to when vaccinating middle-aged and elderly people? Tan Qin, Deputy Chief Physician of General Practice at Sanlin Kangde Community Health Service Center in Pudong New Area, Shanghai, emphasized three key words: age, protective efficacy, and contraindications. Firstly, age and the applicable age of different vaccines vary. Secondly, attention should be paid to the protective efficacy of vaccines, which means the degree to which vaccination reduces disease risk. Vaccines from different technical routes have differences in protective efficacy. Finally, attention should be paid to the contraindications of vaccination. Patients with immune function defects or immunosuppressive diseases cannot receive attenuated live vaccines. For patients with rheumatic and autoimmune diseases, it is recommended to first receive inactivated vaccines and recombinant protein vaccines, "she said. Regarding the concerns of some middle-aged and elderly people about adverse reactions after vaccination, Tan Qin reminds that "common adverse reactions are divided into local and systemic. Local reactions are generally redness, swelling, heat, and pain at the vaccination site. Systemic reactions include fever, loss of appetite, fatigue, etc. These symptoms are usually mild and will disappear on their own within a few days, so there is no need to worry excessively