Sitting for a day is a true portrayal of many office workers. Recently, the related topic "sedentary may increase the risk of diabetes" quickly triggered a heated debate. Many netizens exclaimed, "Knowing that sedentary is not good for health, but how can it be related to diabetes?" The reporter learned that the current research shows that sedentary does increase the risk of diabetes, mainly related to obesity and insufficient insulin sensitivity. Tang Wei, director of the Department of Endocrinology and the diabetes Center of Jiangsu Provincial Government Hospital, told the reporter that the sedentary crowd is in a relatively static state most of the time. On the one hand, due to less physical activity, it is easy to lead to overweight and obesity, and obesity itself is a high-risk factor for diabetes; On the other hand, from the perspective of the pathogenesis of diabetes, it is related to the decrease of insulin sensitivity (also known as insulin resistance). Staying still for a long time will reduce or slow the circulation of peripheral tissues, and reduce the ability to absorb and use glucose, thus increasing the risk of diabetes. In addition to sedentary, low physical consumption and other reasons, experts pointed out that these risk factors for diabetes should also arouse vigilance. "There is a kind of skin melanosis common in the neck or armpit, which is called acanthosis nigricans, and is common in obese patients with insulin resistance." Tang Wei explained that "acanthosis nigricans is not only skin darkening, but also accompanied by skin thickening, roughness and small bulges. Generally, teenagers are more common than adults, and may often indicate endocrine diseases accompanied by insulin resistance." In addition, patients with family history of diabetes, hypertension, dyslipidemia, polycystic ovary syndrome, etc. are also high-risk groups of diabetes. "The family clustering of diabetes is very obvious. An old lady was interviewed before, and two of her three children were definitely diagnosed with diabetes, and the other was pre sugar." Director Tang said that if one parent suffers from diabetes, the risk of children's disease will increase by 20%; Both parents have diabetes, and the risk of children's disease will increase by 50%. "In addition, the birth weight of the baby is too large (the weight of the giant baby is more than 4 kg), which is also a risk factor for diabetes, and the probability of getting sick will be higher in the future." He stressed that the baby mother during pregnancy should also control her weight. If the blood sugar is high during pregnancy, she will be more likely to suffer from diabetes in the future. Experts pointed out that not only lifestyle, genetics, diseases and other factors, but also drug use may increase the risk of diabetes. "Lupus erythematosus patients are more likely to develop diabetes after long-term use of hormone drugs." Director Tang said that this is very common in clinical practice, mainly related to the use of two types of drugs, one is steroids, glucocorticoids, etc; Another type is long-term treatment with psychiatric or antidepressant drugs. In daily life, there is another high-risk situation that is easily overlooked. "If you are over 40 years old and your blood sugar is found to be on the high side in the physical examination, although it has not yet reached the standard of diabetes, it has been higher than the normal level, and you must pay attention to it." Director Tang reminded that for high-risk groups of diabetes, even if there are no typical symptoms such as "three more or less", that is, drink more, urinate more, eat more and lose weight, you should also check your blood sugar level regularly. "Daily sitting should also be avoided, and it is recommended to get up and exercise for a few minutes every hour. The diet should be balanced, maintain weight, and avoid obesity." (Xinhua News Agency)