A new chip that utilizes blood to generate electricity and measure conductivity can quickly monitor health conditions

2024-06-26

According to a recent paper published in the journal Advanced Materials, researchers at the University of Pittsburgh in the United States have developed a new device that can use blood to generate electricity and measure blood conductivity. This innovation will contribute to the further popularization of medical testing. Blood conductivity is an important indicator for evaluating health status, mainly determined by the concentration of basic electrolytes, especially sodium ions and chloride ions. These electrolytes are an indispensable part of many physiological processes and help doctors accurately diagnose diseases. Researchers explain that blood is essentially a water-based environment with various molecules that conduct or hinder electrical currents. For example, glucose solution has certain conductivity, and the condition of diabetes can be judged by measuring its influence on conductivity. Although human blood conductivity is very important, due to measurement difficulties, people have limited understanding of blood conductivity. Measuring conductivity at frequencies below 100 Hz is particularly important for gaining a deeper understanding of blood electrical properties and basic biological processes, but it is challenging. The research team has proposed an on chip laboratory device for nanogenerators with nanofluids, which can measure low-frequency blood conductivity. There is an integrated triboelectric nanogenerator (TENG) in this device that can convert mechanical energy into electrical energy using blood. This process involves electronic exchange between contact materials. In TENG systems, electron transfer and charge separation generate voltage differences, which drive current. The research team analyzed the voltage generated by the device under predefined load conditions to determine the conductivity of the blood. They also use artificial intelligence models to directly estimate blood conductivity through voltage patterns generated by the device. The research team compared the results of the device with traditional testing, demonstrating its high accuracy. In addition, this device can be operated anywhere in the body where blood is present, using local blood for self powered diagnosis. Blood is composed of plasma and blood cells of different shapes suspended within it, and the fluid between these blood cells can be regarded as an electrolyte. For ordinary people, blood conductivity is a somewhat unfamiliar term. In fact, it is related to hematocrit, erythrocyte sedimentation rate, and blood rheology, and therefore is also related to the physiological and pathological state of the human body. In this article, researchers have creatively invented a blood driven detection device that uses the detected object as its own power source. In this way, blood conductivity testing can be applied in more areas where basic medical facilities are lacking, allowing more people to enjoy the benefits brought by advances in medical technology. (Lai Xin She)

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