"Digital Life" Technology Implies New Opportunities in the Health Industry

2024-06-04

The interdisciplinary cooperation between biotechnology (BT) and information technology (IT) is one of the core features of the new round of industrial transformation. The utilization and value realization of digital life resources are important components of new quality productivity and new quality production materials. According to recent research by reporters, China has favorable conditions for developing the digital life industry. We should strengthen our forward-looking layout, further accelerate the research and development of underlying technologies, improve relevant policies, and promote the coordinated development of the upstream and downstream of the industrial chain. The industrial chain covers three major technology clusters. In the laboratory of Carbon Cloud Intelligence Company located in the Zhuhai Hengqin Guangdong Macao Deep Cooperation Zone, a series of complex precision instruments, including lithography machines, are producing a special type of chip - the second-generation silicon-based peptide chip. This chip can synthesize up to 168 million micro detection units on a single 8-inch silicon wafer. The detection sensitivity of each detection unit is hundreds to thousands of times that of existing standard methods, and the sample and reagent consumption is only about one percent of existing standard methods. In other words, it can better "understand" the human body in the field of molecular biology, thereby achieving multidimensional understanding of individual and public health status. This is a part of the entire industry chain of "digital life" constructed by carbon cloud intelligence. According to the founder of the company, Wang Jun, digital life is an emerging concept that reproduces, models, and simulates life information based on carbon based biomolecules and biological interactions in computer systems, facilitating the use of computational technology to study complex biological processes. Digital life is also one of the application areas of Guangdong's future life and health industry layout. Wu Dongwen, Deputy Director of the Guangdong Provincial Department of Industry and Information Technology, stated that by 2030, the five major industrial clusters of electronic information, future intelligent equipment, future life and health, future materials, and future green and low-carbon industries will become new economic growth points in Guangdong. The digital life new technology industry chain mainly includes three new technology clusters: reading, understanding, and using life. "Reading" refers to the process of digitizing life information in all aspects and throughout its lifecycle. "Understanding" refers to integrating the above data, establishing corresponding models, and effectively classifying, inferring, and predicting life activities and biological processes. "Using" refers to discovering new biological knowledge, developing new diagnostic techniques, intervention techniques, providing individual health care plans, and other new medical and health applications based on the above model. He Fuchu, an academician of the CAS Member, believes that unlike traditional biomedicine, which focuses on the status quo, the model constructed by digital life makes accurate prediction, accurate monitoring, accurate early warning and accurate prevention possible. Digital life is expected to transform the "health" industry, which aims to maintain a good state of life and avoid getting sick or getting sick late, from the "medical" industry, which aims to treat and save people, diagnose and treat diseases early, and alleviate disease progression, into a new form of industry, achieving true full cycle coverage of the national health industry. Li Yingrui, co-founder of Carbon Cloud Intelligence, believes that digital life, as a representative of new productive forces, is different from the traditional diagnosis and treatment model of seeking medical treatment. It no longer relies on the expansion and investment of a large amount of medical resources, but through major breakthroughs in basic research in life science and computational science, with risk assessment and proactive health as the main goals, explores the fundamental disruption of the original medical route, and forms a group of disruptive and innovative technology groups. The leapfrog development has unique advantages. Industry experts say that in recent years, a series of breakthroughs in life sciences and biomedical engineering, represented by gene sequencing, protein and peptide array chips, have made it possible to collect large-scale, high-quality digital life basic data at a lower threshold; The rapid popularization of various applications of intelligent devices has led to the digitization of social life, making it possible to collect individual behavioral data; The booming development of cloud computing and artificial intelligence has provided possibilities for the storage, analysis, display, and industry application support of biomedical omics big data. From a global perspective, the concept and industrial development of digital life are flourishing. Major developed countries regard the cross-border integration of bioeconomy and artificial intelligence as an important measure for industrial development, and use the power of the state and government to promote industrial development and conduct forward-looking research layouts. Public information shows that Obama's State of the Union address on precision medicine in early 2015 ignited the enthusiasm of countries around the world for genomics based scientific research and market promotion. The European Union is making efforts to establish a unified e-Health system, investing over 6 billion euros in 10 years. Canada is also planning an EHRS blueprint, aiming to comprehensively promote national medical informatization and the construction of electronic health records. In 2012, the UK launched the 100000 Genome Project with the support of then Prime Minister Cameron, which will sequence the entire genome of 100000 cancer, rare diseases, and infectious disease patients included in the UK's National Health Service (NHS). The goal is to provide personalized and precise treatment to patients through the characteristic correlation between diseases and genes. Experts such as He Fuchu believe that China has unique advantages in achieving comprehensive health, building a new individual oriented health industry pattern with multi-level personal health data as the core, and building a healthy society. There is a possibility of achieving leapfrog development. Scientifically, China's life big data collection and analysis technology is at the world-class level, and related experimental technologies are also at the forefront of the world; Technically, China's information technology and data technology industries have made significant progress, providing a potential support platform for the data centered life and health industry; In terms of industrial structure, compared to developed countries with mature traditional models, China has lower conversion costs and may quickly break through barriers to achieve a more forward-looking new health industry pattern. Experts interviewed believe that we should fully recognize China's special advantages and make forward-looking strategic arrangements to overcome difficulties in the research and development of underlying technologies. Li Yingrui stated that the detection technology of digital life starting from the genome needs to continuously promote breakthroughs in more omics detection methods in order to detect potential risks earlier. It is recommended that the country increase key support for technological innovation at the bottom of the digital life industry, overcome difficulties, improve whole omics detection methods, and provide more and more effective digital life data output. He Fuchu believes that innovative technology alliances and industry alliances should be established within the industry, and key technological breakthroughs and innovations should be solved through the joint efforts of government, industry, academia, research and application. It is recommended to include the proteomics research of domestic life technology enterprises in the proteomics major science program currently being led by China, and to build an open technology platform through key technologies to empower other enterprises and provide assistance for major breakthroughs in proteomics research. Wang Jun suggests encouraging innovative, high-throughput, and large-scale data detection technologies, establishing new regulatory standards for the health industry with the purpose of risk screening and preventive intervention, accelerating the approval process for experimental testing and application of new technologies, allowing pilot areas to take the lead and quickly transform leading technologies into leading applications and data, thereby quickly occupying the industrial highlands. In addition, experts also suggest promoting upstream and downstream collaboration in the industrial chain and creating a new model of digital life economy. For example, by creating significant downstream demand, driving the development of the upstream health data generation industry, and encouraging the clustering and landing of various instruments, reagents, and service providers for biological sample collection, processing, and data production. The breakthroughs in key technologies will drive the coordinated development of the entire industry chain, such as the rapid mass production and application of biochips, which will quickly drive the development of a series of supporting industries such as wafer processing, lithography machines, photoresists, high-definition photography, and bring about industrial linkage. (Lai Xin She)

Edit:He Chuanning    Responsible editor:Su Suiyue

Source:Economic Information Daily

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