It seems like there are often doubts when taking medicine, even after reading the instructions, they still don't understand how to take the medicine. The drug instructions say "take on an empty stomach", what exactly is an empty stomach? Do you have to be so hungry that your stomach growls? Is there any effect if I take medicine after eating? Can you take an extra piece of antipyretic medicine that doesn't work after taking it? Can you switch to other fever reducing drugs? Today, we will answer these questions one by one for everyone, so that everyone can use them effectively and correctly. The more antipyretic drugs you take, the faster the fever will subside? Recently, the temperature has been unpredictable, with a high incidence of respiratory diseases. Coughing and fever are common, and many people's first reaction after a fever is to take antipyretic medication, hoping to recover soon. Regarding fever and fever reduction, you should know the following knowledge points: fever (fever) refers to an increase in body temperature beyond the normal range. Usually, fever is defined as oral temperature ≥ 37.3 ℃ or axillary temperature ≥ 37 ℃. This is just a reference value because everyone's basal body temperature varies. Especially for babies, in addition to checking their body temperature, it is also important to observe whether they have any abnormal symptoms, such as discomfort, emotions, and strength. Fever is not a disease, but a symptom. The first step in dealing with fever is to identify the cause of the fever. It is not recommended to treat fever without authorization until the cause is identified. 1. The commonly used drugs for reducing fever include acetaminophen, ibuprofen, aspirin, acetaminophen, and nimesulide, among which the latter three are generally not allowed to be used in children. 2. It is not recommended to use acetaminophen combined with ibuprofen for antipyretic medication, nor is it recommended to use acetaminophen and ibuprofen alternately for antipyretic treatment. Although combination or alternating use may be more effective, the above methods do not improve comfort, and it is not yet clear whether this temperature reduction has clinical significance. In addition, there is limited security information regarding joint or alternate use. Due to the different dosages of acetaminophen and ibuprofen, administration errors can easily occur. Therefore, it is not recommended to use the two in combination or alternately. The therapeutic effect can generally be observed within 60 minutes of medication and reaches its peak within 3-4 hours. If the body temperature remains high and discomfort does not improve after 3-4 hours of taking acetaminophen, acetaminophen can be directly replaced with ibuprofen. If the body temperature remains high after 3-4 hours of taking ibuprofen and the discomfort symptoms do not improve, ibuprofen can also be directly replaced with acetaminophen. This phenomenon may be related to the better effect of certain fever reducing drugs on only one type. It should be noted that replacing acetaminophen with ibuprofen or ibuprofen with acetaminophen is a simple drug replacement and not an alternate use. Drug replacement vs. drug alternation: Taking Tylenol (acetaminophen) and Ibuprofen as examples to supplement the explanation: Drug replacement: After replacing Tylenol with Ibuprofen, if it works, continue to use Ibuprofen and no longer use Tylenol. Alternating use: After Tynolin, use ibuprofen, then use Tynolin, and then ibuprofen,