Recently, 43 year old Ms. Zhang was plagued by oral odor and only found out after visiting the hospital that it was caused by Helicobacter pylori. What is Helicobacter pylori? What are the symptoms of Helicobacter pylori infection? What hazards will occur? To raise public awareness of Helicobacter pylori, May 15th every year is designated as the National Day without Helicobacter pylori. Experts also remind that people with a family history of peptic ulcers, gastric cancer, and other conditions who are infected with Helicobacter pylori should be cured as soon as possible. Recently, Ms. Zhang has always felt a "strange smell" in her mouth. When talking to others, people around her can clearly smell it, which has brought great trouble to her life. So she went to the dental department for teeth cleaning and oral medication, but after treatment, there was still no improvement. She suspected digestive problems and went to the outpatient department of the Gastroenterology Department of Jiangsu Province Integrated Traditional Chinese and Western Medicine Hospital for treatment. According to Ms. Zhang's symptoms, Li Hui, the deputy director and chief physician of the department, suggested that she first complete a 13C breath test to detect whether she is infected with Helicobacter pylori, and the result showed a positive result. Ms. Zhang was greatly surprised and filled with doubts, as she had almost no knowledge of Helicobacter pylori before. Director Li Hui provided her with a detailed education on Helicobacter pylori and explained to her the treatment plans for subsequent eradication. After persistently taking the medication for 2 weeks, Ms. Zhang's oral odor significantly decreased. After stopping the medication for 1 month, a follow-up 13C breath test showed a negative result. It is understood that Helicobacter pylori is a bacterium associated with various stomach diseases and is also the main cause of gastric cancer in China. The most appropriate way to describe the transmission of Helicobacter pylori (Hp) is through the mouth, fecal oral transmission, and water source transmission. Oral transmission may be one of the main ways for family members to become infected. While enjoying a happy meal together, it is possible that Helicobacter pylori has quietly come to their doorstep. Experts explain that most infected individuals have no symptoms or complications, but almost all Helicobacter pylori infected individuals have chronic active gastritis, which is closely related to various stomach diseases such as peptic ulcers, chronic atrophic gastritis, and gastric cancer. 25% -30% of infected individuals will experience varying degrees of gastrointestinal diseases, manifested as oral odor, nausea, upper abdominal pain, and indigestion. The occurrence of oral odor is mainly due to the fact that when Helicobacter pylori resides in the epithelium of the digestive tract, it decomposes urea to produce ammonia gas to protect itself from gastric acid damage. At the same time, Helicobacter pylori itself also produces hydrogen sulfide and methylthiol, both of which can also cause bad breath. Currently, it is believed that Helicobacter pylori infection is the most important and controllable risk factor for gastric cancer. Eradicating Helicobacter pylori can reduce the risk of gastric cancer in China and effectively prevent it. However, it is not realistic to proactively screen all Helicobacter pylori positive individuals for treatment at this stage. However, experts remind that for patients infected with Helicobacter pylori who meet the following indications, such as peptic ulcers, gastric mucosa associated lymphoid tissue lymphoma, chronic gastritis with digestive symptoms, it is recommended to undergo eradication treatment. (Lai Xin She)