The major cross regional and cross sectoral strategy needs to be promoted in a coordinated manner by multiple regions and departments, and plays a decisive role in comprehensively promoting the building of a strong country and national rejuvenation with Chinese path to modernization. The Third Plenary Session of the 20th Central Commission for Discipline Inspection has made "improving the collaborative supervision mechanism for major strategies across regions and departments" an important part of strengthening political supervision. Disciplinary inspection and supervision organs should strengthen their systematic concept, take proactive actions and act in a mutually beneficial manner, deepen linkage supervision, closely cooperate and cooperate, improve work mechanisms, and promote the implementation of major strategies across regions and departments through regular and long-term political supervision. Strengthening the consciousness of "playing a game of chess", clenching fingers into fists, and consolidating joint strength. Cross regional and cross departmental major strategies are closely planned and implemented around global and long-term issues, connecting the east, west, and east, coordinating the north and south, and coordinating land and sea areas. Disciplinary inspection and supervision agencies (institutions) in relevant regions and departments should effectively improve their political stance, consciously find the positioning of collaborative supervision in the overall cause of the Party and the country, strengthen the system concept, break the "one acre, three parts" thinking, work together and resonate with the same frequency, "efficiently do their own things, actively organize common things, and actively serve others." They should integrate political supervision into all aspects of the entire process of strategic implementation, consolidate the full chain responsibility with high-quality collaborative supervision, and promote the full implementation of strategic deployment. Guided by special supervision, we will focus on concretization and precision. Political supervision can only be effective if there is a lever. For the regions and departments involved, major national strategies are guiding strategies related to development direction, with corresponding implementation plans and specific policies. Disciplinary inspection and supervision organs should strive for depth with specificity and effectiveness with precision. They should compare major projects, key tasks, and important measures for collaborative development, and focus on common and prominent regional issues. They should sort out and clarify supervision matters in a hierarchical and graded manner, clarify the responsibility chain item by item, and form a list of collaborative supervision tasks and responsibilities. They should calibrate and update according to the time and situation, clearly list the objects, content, and standards one by one, making the probe more focused and the supervision more precise. We will focus on improving the operability and pertinence of cross regional linkage, with major special supervision as the driving force, strengthen collaboration and cooperation with relevant regions and departments, carry out joint inspections around common supervision matters, implement list based management and project-based promotion, and promote the deepening and implementation of collaborative supervision work. Focusing on the long-term effect of normalcy and improving the mechanism of collaborative cooperation. Major strategies should be based on the overall situation and have a long-term perspective. Once formed, they must be adhered to in the long run and grasped to the end. Strategic execution is a long-term process that determines that collaborative supervision must be carried out regularly. We need to give full play to the fundamental and long-term role of institutional management, and make efforts to improve the collaborative supervision mechanism. Exploring the establishment of a regional collaborative supervision system based on river basins in the areas along the Yangtze River and Yellow River, as well as the disciplinary inspection and supervision agencies (institutions) of water conservancy departments, and deepening the use of the communication and coordination mechanism for disciplinary inspection and supervision of water conservancy along the Yangtze River and Yellow River, to ensure the joint efforts of the system to safeguard national rivers