For a long time, the small and dense font, obscure and difficult to understand content, and cumbersome information on drug instructions have been a problem for every drug user, especially for elderly and disabled patients. The "small as ants" drug instructions not only greatly increase their difficulty in understanding drugs, causing reading difficulties, but also pose certain risks and hidden dangers to safe and rational medication for patients. As a special commodity, drugs are closely related to the lives of the people, and drug instructions, as a legal guide for selecting drugs, should be very standardized and detailed. According to the "Regulations on the Administration of Drug Instructions and Labels" implemented in June 2006, drug instructions should include important scientific data, conclusions, and information on drug safety and efficacy. Especially for the internal labeling of drugs, according to regulations, it should include the general name of the drug, indications or functional indications, specifications, usage and dosage, production date, product batch number, expiration date, production enterprise, etc. With the increasingly standardized management of drug instructions, the content in the instructions is becoming more comprehensive. A large amount of professional and lengthy scientific information can only be written on one piece of paper, and the font size is inevitably limited. From the perspective of medication safety, in clinical practice, it is common to encounter cases where patients fail to carefully read the instructions, or fail to understand or label them prominently, resulting in adverse consequences. For example, some drugs have inconsistent units of content and dosage, requiring conversion; Some are tablets or capsules, but the dosage is in milligrams; Some children take medication based on their weight; The number of days marked as "avoid drinking alcohol and alcoholic beverages during and after medication" often leaves patients confused. How to make drug instructions both professional and applicable, to better ensure patient safety and rational medication? At the end of 2023, the National Medical Products Administration announced the first batch of pilot lists for aging and accessibility reform of drug instructions. As of now, 270 drugs have been registered nationwide. It is expected that the first batch of pilot drugs will gradually be launched on the market by the end of June this year, and drug instructions will undergo aging friendly and barrier free reforms. This latest simplified version of the instruction manual, on the one hand, has reduced the word count by nearly 50% compared to the old version based on the different needs of different patient groups and the differences in the specification content of various drug packaging. The font has changed from small five to small three, while retaining important information such as ingredients, characteristics, functions, and indications. To some extent, it solves the above problems, emphasizing professionalism while meeting convenience; On the other hand, by continuously improving the management system, enhancing the popularization of medical and pharmaceutical science popularization, using medication reasonably under scientific guidance, ensuring patient medication safety, strengthening medication guidance services for patients, and also reducing doctor-patient disputes caused by medication instructions. The modification of drug instructions may seem like a small matter, but in reality, it is a crucial matter that concerns the happiness and safety of drug users, especially elderly patients. The first step is to make the instructions clear to patients, and it is even more important for everyone to be able to read them clearly. How to improve basic public health services and better meet the health needs of the people, and subsequent improvements