Should I drink cold water or hot water when taking medicine when I'm sick? Can tea or beverages be used instead? In fact, there are also considerations regarding the amount of water used for medication. The type of water used, the amount of water used, and the temperature of the water can all affect the efficacy of the medication. Don't choose these types of medication for delivery. Warm water is preferred. Except for special medications, it is generally not recommended to use tea, fruit juice, milk, or alcohol for medication. Tea contains a large amount of tannins, which can easily interact with the ingredients in drugs. For example, taking drugs to treat iron deficiency anemia (such as iron fumarate, ferrous sulfate, etc.) with tea can cause precipitation, affect iron absorption, and lead to a decrease in drug efficacy. At the same time, tea also contains ingredients such as caffeine and theophylline, which have an excitatory effect on the central nervous system and can affect the effectiveness of sedatives and hypnotics. Juice juice is rich in fruit acid, which can react chemically with some drugs and is not conducive to drug absorption. Grapefruit juice can increase the bioavailability of antihypertensive drugs (such as felodipine, nifedipine, and nicardipine), leading to symptoms of hypotension. The calcium content in milk is relatively high. When some antibiotics (such as tetracycline, ceftriaxone, norfloxacin, levofloxacin, etc.) are taken together with milk, they will react with the calcium in milk to form insoluble chelates, reducing the antibacterial effect, reducing the efficacy of the drugs, and even completely rendering them ineffective. Alcohol may affect the metabolic processes of various drugs in the body. If some cephalosporin drugs (such as ceftriaxone, cefoperazone, etc.) are taken during alcohol consumption, it may induce disulfiram like reactions, and in severe cases, it can lead to death. When taking most tablets and granules, you can first take a sip of water to moisten your throat, and then use 150-200 milliliters of water to take. Some drugs require a large amount of water when taken, such as sulfonamide drugs and antibacterial drugs such as levofloxacin and moxifloxacin. The solubility of their metabolites in urine is low, and anti gout drugs can promote uric acid excretion. Patients should drink more water when taking these drugs to avoid crystallization and causing urinary system stones. The commonly used antipyretic and analgesic drugs for colds and fevers (such as ibuprofen) can cause excessive sweating after taking them. Drinking more water can help prevent dehydration. Bisphosphonates used to treat osteoporosis, such as sodium alendronate, have side effects that irritate the upper gastrointestinal mucosa. It is recommended to take them with approximately 200 milliliters of water. Some drugs have a unique way of taking effect, so it is important to drink less water when taking medication. Gastric mucosal protectants (such as sucralfate, aluminum hydroxide, etc.) and antidiarrheal drugs (such as montmorillonite powder, etc.) both have therapeutic effects by covering the digestive tract mucosa. Syrup cough suppressants need to adhere to the throat to exert their effects. Patients should try not to drink water after taking these drugs to avoid washing away the drugs that adhere to the corresponding area and affecting the therapeutic effect. The temperature of water varies and has an impact on the efficacy of some drugs. It is usually best to take warm water at 40-50 degrees Celsius. If the water temperature is too high, some drugs may undergo physical or chemical reactions when exposed to heat, which can affect the therapeutic effect. Digestive aids, such as pepsin, trypsin, amylase, multienzyme tablets, lactase, yeast tablets, compound digestive enzymes, live bacterial preparations, etc., are mostly enzymes and active ingredients in these types of drugs