"China has established a mouse model sensitive to monkeypox virus. The construction of non-human primate models of monkeypox virus has also made great progress." At the recent China Conference on the Development of Experimental Animal Science, Peng Xiaozhong, Director of the Institute of Medical Experimental Animals and Director of the National Animal Model Technology Innovation Center of the Chinese Academy of Medical Sciences, introduced that animal models will provide technical support for the development of monkeypox vaccines and related drugs. In sudden public health emergencies, animal experimental research is the "speed limit" link in vaccine and drug development. Vaccines, antibodies, drugs, etc. developed for pathogens must be validated on animal infected individuals before clinical research can be conducted. The ability to construct animal models is an indispensable part of the rapid response system in technology. To this end, multiple departments are working together to build China's national animal model innovation system. To promote the overall leap of innovation in the field of animal models in China, with the support of government departments such as the Ministry of Science and Technology and the National Health Commission, the National Animal Model Technology Innovation Center (hereinafter referred to as the "Innovation Center"), led by the Institute of Medical Experimental Animals of the Chinese Academy of Medical Sciences, has been launched. "Establishing an animal model technology innovation center in the pharmaceutical field will provide important technological support for enhancing China's experimental animal research capabilities and promoting high-quality development of medicine." Vice Minister of Science and Technology Chen Jiachang pointed out that the innovation center should focus on important tasks such as creating animal models for major diseases, clinical testing of vaccines and drugs, and platform construction, and produce original and breakthrough achievements. While closely aligning with the technological needs of enterprises and promoting the transformation of cutting-edge technological achievements, explore multi-party collaborative models and strengthen the open sharing of innovative resources. Zeng Yixin, Deputy Director of the National Health Commission, emphasized that experimental animals are the foundation of all scientific research, and the construction of innovation centers should benchmark against the most advanced international standards, target bottleneck issues that restrict the development of life sciences and health research, and lead the development of experimental animals and model animals nationwide. "The Innovation Center will coordinate national strengths, promote effective collaboration, form a joint force, and provide high-quality source technology supply for animal models." Peng Xiaozhong introduced that in accordance with the deployment requirements of the Ministry of Science and Technology, the Innovation Center has launched the operation and construction of sub centers and is planning to deploy bases such as non-human primate resources, small pig resources, chronic disease animal models, and drug transformation platforms in Beijing, Hebei, Tianjin, Hainan, and other places, And coordinate with local governments and medical schools to explore new models of co construction and sharing. Aiming at bottlenecks and carrying out core technology research, "In medical and biological research, experimental animal models have a guiding and guiding role that cannot be replaced." Academician Wang Chen, Vice President of the Chinese Academy of Engineering, President of the Chinese Academy of Medical Sciences, and President of Beijing Union Medical College, introduced that animal experiments play an important role in deducing and "projecting" humans. At the same time, there is still an insurmountable comparative biology gap between humans and animals, and the logic between them needs further research. Peng Xiaozhong also stated that model animals, as "animal patients," can help researchers conduct systematic dialectical research from the surface to the inside, thereby revealing disease patterns and elucidating disease mechanisms. However, due to the differences between animals and humans