The Central Economic Work Conference recently held at the Guangming Forum has set the tone for economic work in 2024, prioritizing the construction of a modern industrial system led by scientific and technological innovation as the top nine key tasks, and emphasizing the strengthening of the leading role of enterprises in scientific and technological innovation. Enterprises are the main body of industry, market, and innovation. Strengthening the position of enterprises as the main body of scientific and technological innovation is a key measure to deepen the reform of the scientific and technological system and promote the realization of high-level scientific and technological self-reliance and self-improvement. Establish a technology innovation system with enterprises as the main body. Strengthening the dominant position of enterprise technological innovation is conducive to promoting the deep integration of innovation chain, industry chain, capital chain, talent chain, and accelerating the industrialization process of scientific and technological achievements. Establishing a sound technology innovation system with enterprises as the main body can bring innovation activities closer to the production line and enable innovation achievements to face market demand. In the perspective of innovation driven strategy, by improving the decision-making consultation mechanism, establishing a mechanism for enterprises to participate in national science and technology strategic decision-making on a regular basis, guiding enterprises to carry out research and development around major national strategic deployments. At the same time, establish a normalized consulting system for entrepreneurial technological innovation, regularly organize communication and exchange, improve resource allocation mechanisms, and promote enterprises to become the main body of research and development investment. On the one hand, we will effectively and orderly promote the "list unveiling and leadership" system, and promote more scientific research tasks to be undertaken by enterprises; On the other hand, we will improve policies that benefit enterprises such as pre tax deduction of research and development expenses, strengthen incentives for enterprise research and development investment, and promote more research and development investment to be contributed by enterprises. In addition, by constructing a gradient cultivation system for technology enterprises, we aim to promote the integrated development of large, medium, and small enterprises. Firstly, establish and improve a gradient cultivation system of "technology-based small and medium-sized enterprises - technology-based backbone enterprises - technology-based leading enterprises - world-class enterprises", and accelerate the cultivation of high-quality enterprises such as unicorn enterprises and specialized and innovative enterprises; The second is to optimize the positioning and layout of technology leading enterprises, encourage them to consciously fulfill their high-level mission of technological self-reliance and self-improvement, and actively undertake national major scientific and technological tasks and key core technology research and development; Thirdly, we will leverage the leading and supporting role of technology-based backbone enterprises to enhance their resource, technological, and financial support capabilities for small and medium-sized enterprises and universities; The fourth is to utilize the flexible and adaptable characteristics of technology-based small and medium-sized enterprises, target their respective sub sectors, increase innovation investment, and proactively layout future industries. Establish a sound research organization model led by enterprises. To break through bottlenecks and solve deep-seated contradictions and problems, the key is to rely on the power of scientific and technological innovation, and continuously promote the modernization of the scientific and technological governance system and governance capacity. By actively exploring new paradigms for the integration of industry, academia, and research, we aim to shift the paradigm of industry, academia, and research cooperation led by universities to that led by enterprises, bridging the gap from technological strength to industrial strength, economic strength, and national strength. At the same time, we will build a group of key technology research projects in the industrial chain, led by leading enterprises and widely participated by universities and colleges, to tackle a number of key core technologies. By establishing industrial technology alliances, supporting enterprises to actively participate in the construction of major innovation scenarios, promoting collaborative innovation between enterprises and universities, and promoting effective integration of achievement supply and industrial demand. In talent cultivation