We should adhere to strengthening regional coordination and integration as the focus, and provinces and cities along the Yangtze River should adhere to inter provincial consultation, ecological co governance, global co construction, and development sharing, enhance regional transportation connectivity, policy unity, rule consistency, and execution synergy, steadily promote the construction of ecological communities and benefit communities, and promote regional coordinated development Practice has proven that strengthening regional synergy and integration is a key strategic approach and approach in promoting this national strategy. In September of this year, the competent commercial departments of Shanghai, Jiangsu, Zhejiang, and Anhui jointly signed the "Agreement on Deepening Market Integration and Business Development Cooperation in the Yangtze River Delta Region" in Beijing. According to the cooperation agreement, the commercial authorities of the three provinces and one city will focus on deepening practical cooperation in promoting market rules and systems, commercial infrastructure interconnection, and sharing of commercial circulation systems. The aim is to accelerate the creation of a more stable, fair, transparent, and predictable business environment, and assist in the construction of a unified national market. This is a beneficial attempt to promote the construction of a unified national market through regional coordination and integration, undoubtedly providing new reference for the development model of promoting regional market integration through regional national strategies. The significance of promoting the construction of a unified national market through regional coordination and integration. Strengthening regional coordination and integration refers to the process of achieving high-quality development characterized by economies of scale and scope through government cooperation and market competition among regions with clear administrative boundaries, continuously eliminating various institutional and institutional obstacles that hinder the free flow of commodity elements and resources within the region. Regional synergy and integration, based on regional market integration, plays a decisive role in promoting the construction of a unified national market from the bottom logical perspective. This is first reflected in the fact that the integration of the market system is the core of overall economic integration and the foundation and key to all integration work. Breaking down institutional and institutional barriers that restrict the free flow of production factors such as land, labor, and capital, encouraging enterprises in the region to fully compete, and using mergers and acquisitions to eliminate ineffective or inefficient assets in the region will have important integration effects. At the same time, industrial clusters are an important spatial carrier and material support for regional collaborative and integrated development, as well as a concrete manifestation of blurring administrative boundaries in regional development and achieving integrated development of regions, industries, technologies, etc. The construction of several advanced manufacturing bases with global influence is a strategic goal pursued by the Yangtze River Delta regional integration countries, and effective interest coordination is needed for the development strategy of industrial clusters. In addition, the development of technological innovation alliances provides core driving force for market integration and technical support for the development and growth of industrial clusters. On a specific path, we need to achieve self alignment, self coordination, and self-development in innovation projects, and build a technology industry innovation center with significant influence on a global scale. Due to the external characteristics of innovation and the limitations of the existing performance evaluation system, there may be some conflicts of interest in practice, but this is an important area that urgently needs to be broken through. By region