Anorexia is a common disease in children, mainly manifested as long-term loss or disappearance of appetite, decreased appetite, or even refusal to eat. If children suffer from long-term anorexia, it can lead to malnutrition, slow growth and development, immune dysfunction, serious impact on physical and mental health, and cause children to be "yellow, thin, and short", which is a problem that parents are very concerned about today. Doctors from the pharmacy department of the Municipal Children's Hospital remind that there are various causes of anorexia in children, and it is necessary to distinguish the situation to respond. There are many trace elements in the human body that play a very important role and are indispensable. Zinc is one of them, participating in the synthesis of various enzymes in the body and playing an important role in taste bud cells, maintaining normal appetite and taste. Zinc deficiency can lead to decreased taste buds function, and a decrease in the zinc content of taste hormones in saliva can make it difficult for food to come into contact with taste buds, which cannot cause taste perception, leading to anorexia, decreased immune function, and increased susceptibility to diseases. Zinc preparations such as zinc gluconate can correct the deficiency of zinc in the body of children, increase the zinc content of taste buds, relieve the barrier between taste buds and food, restore the sensitivity and function of taste buds, and thus increase appetite, which is beneficial for the recovery of the body and digestive function. Promoting gastric motility drugs can enhance gastrointestinal motility, promote peristalsis of the gastrointestinal tract, restore its normal tension, promote gastric emptying, and are beneficial for promoting gastric digestion and increasing appetite. The combination of these drugs with zinc gluconate has a synergistic effect on the treatment of pediatric anorexia and promotes the improvement of long-term anorexia. However, it should be noted that such drugs should be used with caution in children, such as domperidone, which may cause dry mouth, headache, insomnia, etc. If taken for a long time, it may lead to serious adverse reactions such as feminization of men's breasts and arrhythmia. Children under the age of 12 should use them with caution. Children are often prone to infectious diseases due to their low autoimmunity, and almost all long-term use of antibiotics will cause intestinal flora disorder, microecological imbalance, resulting in abdominal distention, nausea and anorexia. Microecological preparations can supplement the quantity of beneficial bacteria in the intestine, correct the imbalance of the gut microbiota, rebuild the normal microbiota balance in the intestine, effectively improve intestinal function, form a biological barrier on the surface of the entire intestinal mucosa, thereby preventing the invasion of pathogenic bacteria, improving the intestinal environment, promoting intestinal peristalsis, reducing the time food stays in the intestine, and giving children a certain sense of hunger to enhance appetite, It has good therapeutic effect and high safety for anorexia. (Reporter Di Hui) (Xinhua News Agency)