How to achieve low energy artificial intelligence? How do crops adapt to soil environment in the context of global climate change? How to break through the application of carbon fiber composite materials in China's future ultra high speed rail transit vehicle equipment? On the 22nd, the China Association for Science and Technology released 10 forward-looking, innovative, and leading cutting-edge scientific issues, 9 engineering and technological challenges, and 10 industrial and technological issues. At the main forum of the 25th China Association for Science and Technology Annual Conference held in Hefei, Anhui, major issues in the fields of artificial intelligence, new energy, high-performance materials, and life sciences received attention. The 29 issues and challenges released by the Chinese Association for Science and Technology at the main forum of the annual meeting also include "how to achieve maneuvering flight of aircraft in the upper atmosphere", "how modern terrestrial ecosystems originated", "how to break through the clean and high-value utilization of new energy waste", "how to apply brain computer interface technology to clinical medicine", and so on. Academician Gao Hongjun, the publisher of major issues and challenges for the year 2023 and Vice Chairman of the China Association for Science and Technology, said that this selection emphasizes the cutting-edge, strategic, innovative, and leading nature of quasi problems, grasping the trend of scientific and technological development and the direction of disciplinary cutting-edge development, and serving scientific and technological workers to contribute to the country and the people. According to reports, this year's solicitation and release event received a total of 590 questions and challenges recommended by 89 national associations and associations, as well as some enterprise science associations, covering ten major fields including basic science of mathematics, physics and chemistry, earth science, ecological environment, manufacturing technology, information technology, advanced materials, resource energy, agricultural technology, life and health, and aerospace technology. The selection process further highlights the guidance of high-level expert evaluation, with 117 academician experts conducting strict evaluation and control in the selection, final selection, and other stages. Since 2018, the China Association for Science and Technology has organized a collection of problem and difficult problem activities for six consecutive years. A group of national societies have established a mechanism for releasing problems and difficult problems in their field, and have conducted academic exchanges, think tank suggestions, science popularization interpretations, and collaborative research around the issues released. The China Association for Science and Technology will continue to track the issues and difficulties released, guide scientific and technological workers to carry out original and leading research, and accelerate the realization of high-level technological self-reliance and self-improvement. (New News Agency)