May 25th is International Skincare Day and also National Skincare Day. The skin is the first physiological defense line and the largest organ of the human body, which can help resist the invasion of foreign viruses and participate in various physiological functions of the body. With the aging of the population in China, the proportion of elderly people attending dermatology clinics is also increasing year by year. Recently, the reporter interviewed relevant experts to provide skincare advice for elderly people over 50 years old. Shi Lei, deputy director of the dermatology of East China Hospital affiliated to Fudan University, pointed out in an interview that the occurrence of skin diseases is related to aging, emotion, sleep, diet, environment, immunity, heredity and other factors. Common skin diseases among middle-aged and elderly people include herpes zoster, atopic dermatitis, viral warts, etc. Among them, herpes zoster is a disease that many people overlook. Shi Lei introduced that herpes zoster is one of the most common severe skin diseases in dermatology, which can form blisters, ulcers and scars. Seriously affecting the quality of life of patients, it can lead to anxiety, depression, lack of concentration, sleep disorders, etc., and in severe cases, even desire to commit suicide. Middle aged and elderly people suffer from immunosenescence. They often suffer from herpes zoster in basic diseases such as fatigue, stress trauma, diabetes, chronic renal insufficiency, cardiovascular disease, chronic obstructive pulmonary disease, etc., which may infect their grandchildren and cause chickenpox. The elderly are often in serious condition, with severe pain that lasts for months to years, and may be accompanied by motor nerve involvement, facial paralysis, muscle strength decline, and blindness. A small number of severe patients develop disseminated herpes zoster, or involve the central nervous system, heart, lungs, liver, kidney, and other internal organs, which is life-threatening. The main treatment methods for herpes zoster include antiviral, anti-inflammatory, analgesic, etc. Within 72 hours of onset, antiviral or specific antiviral drugs are effective. However, most patients often fail to receive timely and effective treatment, resulting in postherpetic neuralgia. Due to the current lack of efficient treatment methods for sequelae neuralgia, it is extremely important to prevent and popularize science for herpes zoster. Shi Lei suggests that middle-aged and elderly people, in addition to skincare and skincare, should have a healthy diet, moderate exercise, avoid fatigue and stress, and actively control chronic diseases. If you suspect herpes zoster, you must seek medical attention from a hospital with experience in diagnosis and treatment as soon as possible. Early targeted treatment such as specific antiviral therapy can also be achieved through vaccination for active immunity. The occurrence of skin diseases may also be related to factors such as emotional sleep, dietary structure and habits, endocrine, immune, and genetic factors. Middle aged and elderly people should pay attention to both internal and external repair, and external skin care and maintenance should be reasonable to delay skin aging. Internally, we should pay attention to health, immunosenescence, and enhance immunity. Cheng Lili, Deputy Director of the Public Health Department of Fenglin Street Community Health Service Center in Xuhui District, Shanghai, introduced that vaccination is an economically effective health management method for disease prevention and a crucial part of the health management process for middle-aged and elderly people. Middle aged and old people can be vaccinated with pneumonia vaccine, influenza vaccine, herpes zoster vaccine, and COVID-19 vaccine. The data shows that the treatment cost for herpes zoster includes outpatient and inpatient treatment costs, over-the-counter drugs, and treatment. It is estimated that the annual cost of new cases of herpes zoster among people over 50 years old is about 1.3 billion yuan, and vaccination can help reduce the overall burden of preventable diseases.