The report of the 20th National Congress of the Communist Party of China has made systematic arrangements for "accelerating the realization of high-level technological self-reliance and self-improvement", "strengthening the dominant position of enterprises in scientific and technological innovation", and "strengthening the deep integration of industry, academia, and research led by enterprises". On April 21, 2023, the first meeting of the 20th Central Committee for Comprehensive Deepening Reform reviewed and approved the "Opinions on Strengthening the Leading Role of Enterprises in Science and Technology Innovation", emphasizing the promotion of the formation of an innovation system with enterprises as the main body and efficient collaboration and deep integration of industry, academia, and research. This further clarifies the important role of enterprises in high-level technological self-reliance and self-improvement, and the in-depth implementation of this opinion requires efforts from multiple aspects. On the one hand, we should deepen reform through multiple approaches and comprehensively strengthen the dominant position of enterprises. Against the backdrop of increasingly prominent global development instability, uncertainty, and insecurity, as well as the combination of "blockages" and extreme risks imposed by the United States and the West on me, and the urgent requirements of comprehensively deepening reform and advancing into deep water areas, stabilizing the overall situation and opening up new situations, and under the theme of high-quality development, it is urgent to take multiple measures to further strengthen the dominant position of enterprises in innovation decision-making, talent gathering, scientific research organization, achievement transformation, value evaluation, and other aspects The role of the subject. To achieve deep integration of industry, academia, and research, and ultimately achieve high-level technological self-reliance and self-reliance, enterprises are duty-bound. At the same time, innovation leading and technological support are the necessary paths for the development of modern enterprises. Regardless of the perspective, strengthening the dominant position of enterprise innovation is an important topic, driving force, and concentrated driving force at present. Strengthen the leading position of technology leading enterprises. In the new era of 10 years, the reforms we have promoted are comprehensive, profound, and fundamental, and the achievements we have achieved are historic, revolutionary, and groundbreaking. At present, a large number of our backbone enterprises have stood at a new historical starting point, firmly holding the dominant power of development in their own hands, forming a new pattern of world modernization development, which has become possible and is forming an irreversible trend. Deepening the reform of state-owned assets and enterprises, accelerating layout optimization and structural adjustment, strengthening and optimizing the development of large capital and state-owned enterprises, and enhancing the core competitiveness of enterprises are urgent tasks to enhance China's core competitiveness. We should further incentivize technology leading enterprises and technology-based backbone enterprises to enhance the endogenous driving force of innovation and strengthen investment in applied basic research. Grant leaders of leading enterprises more resource allocation rights, industrial alliance construction rights, and discourse power in industry standard formulation. Support the "two" to play a greater role. The fundamental driving force of innovation lies in talent leadership, and the key to talent leadership lies in cultivating strategic scientists and strategic entrepreneurs ("two") who adapt to the new requirements of the modern industrial system and the new needs of enterprise independent innovation. Give the "two" more participation rights in major science and technology project initiation, major science and technology infrastructure construction, and gradually form a new situation where technology leaders and backbone enterprises collaborate with universities and research institutes to promote the implementation of major projects, fundamentally solving the long-standing problems of poor cooperation between industry, academia, and research, weak industrial foundation, and difficult transformation of scientific and technological achievements in China. Support enterprises to become basic research subjects. Fully leverage the role of enterprises as "problem solvers," "answer takers," and "reviewers" in applied basic research, accelerate the reform of national key laboratories, and support the establishment of more major technology platforms in leading enterprises. strengthen