On April 20th, the first live attenuated herpes zoster vaccine suitable for people aged 40 and above in China was administered for the first time nationwide in Changchun, Jilin, marking the official launch of nationwide vaccination of the domestic herpes zoster vaccine. Shingles is a non fatal but painful disease. Have people around you ever had shingles? This disease is commonly known as "Huolong Waist", but it may also occur in other parts of the body. According to Wu Bin, director of the dermatology of the People's Hospital of Jilin Province, herpes zoster is the most common infectious diseases in the dermatology at present, which mainly occurs in adults over 40 years old. In recent years, the incidence of this disease has shown a trend of youthfulness, with many young people experiencing weakened immunity due to reasons such as working overtime or high life pressure, which has led to the occurrence of this disease. The biggest characteristic of herpes zoster is pain, like a knife cut, electric shock, or acupuncture. The most common sequela of herpes zoster is postherpetic neuralgia, with pain levels up to 10 degrees. Patients often have difficulty sleeping and eating during attacks, which seriously affects their quality of life and can last for months or even years. The consensus of experts on herpes zoster vaccine prevention and vaccination points out that currently, the treatment of herpes zoster is mainly based on antiviral and symptomatic treatment, and there is no specific drug available. The cause of the disease is varicella virus, which was infected in childhood. Wu Bin, director of the dermatology of Jilin Provincial People's Hospital, said that the cause of herpes zoster is very simple. It is derived from the "varicella zoster virus" that the patient was infected with when he was a child. This virus will hide in the dorsal root ganglion of the human central nerve. As age increases or due to internal and external factors such as fatigue and trauma, the immune system decreases. This virus is reactivated, replicated, and propagated in the body, migrating along nerve fibers to the surface of the skin, manifested as herpes zoster. The disease is one of the common infectious diseases of the middle-aged and elderly. Vaccination is the most effective and feasible preventive measure. Vaccination against herpes zoster is the most cost-effective and effective way to prevent it. The launch of domestically produced herpes zoster vaccines has broken the dependence on imports for herpes zoster vaccines, becoming the first live attenuated herpes zoster vaccine suitable for people aged 40 and above in China. With just one dose of immunization, it can provide vaccinators with more than 10 years of immune effect. With continuous access from all over the country, the majority of eligible age groups can receive domestic herpes zoster vaccines at nearby vaccination clinics. (New News Agency)