Over the past nine years, along the direction of the General Secretary, the Beijing-Tianjin-Hebei coordinated development strategy has profoundly changed the land of Beijing-Tianjin-Hebei. Since the Beijing-Tianjin-Hebei coordinated development strategy was put forward, China has issued a series of major regional strategies, such as the development of the Yangtze River Economic Belt, the construction of the Guangdong-Hong Kong-Macao Greater Bay Area, the integrated development of the Yangtze River Delta, the ecological protection of the Yellow River basin and high-quality development, which has become an important support for China's economic development pattern. Regional economy is an organic part and an important spatial carrier of Chinese path to modernization, and the unique characteristics of Chinese path to modernization will deeply affect the mode and path of regional economic development. At present, major regional strategies are an important focus of China's regional economic development, and Chinese path to modernization construction urgently needs to play the leading role of major regional strategies. To promote Chinese path to modernization with major regional strategies, the macro level should be based on the new development stage, practice the new development concept, and build a new development pattern. The transformation of China's economy from a stage of rapid growth to a stage of high-quality development requires the cultivation of new drivers and the construction of new growth poles. Key regions are important engines to drive and lead China's economy to accumulate energy and achieve stability. Solving the development problems of key regions is related to the overall situation of promoting high-quality development in China. At present, a series of major regional strategies under implementation in China, such as the coordinated development of Beijing Tianjin Hebei, the development of the Yangtze River Economic Belt, the construction of the Guangdong Hong Kong Macao Greater Bay Area, the integrated development of the Yangtze River Delta, the ecological protection and high-quality development of the Yellow River Basin, fully demonstrate the new development concept of innovation, coordination, green, open and sharing, which is highly consistent with the essential characteristics of Chinese path to modernization. One of the core points of the major regional strategy is to promote the development of regional integration and promote the free flow and optimal allocation of resources between regions. Under the influence of major regional strategies, China is gradually forming a comprehensive, multi-level and wide-ranging regional linkage pattern. By breaking the regional division and promoting the construction of a unified national market, China further releases the potential of the super-scale market, which has injected a strong impetus for building a new development pattern and achieving high-quality development. To promote the construction of Chinese path to modernization with a major regional strategy, at the meso level, it is necessary to deeply grasp the differentiated characteristics of different regions in China, grasp the key regions and key issues, give play to the radiation and driving role of developed regions and central cities, and truly achieve the goal of "getting rich first and driving wealth later". The main contradiction in our society has been transformed into the contradiction between the people's growing need for a better life and the unbalanced and inadequate development. For this reason, it is necessary to further promote major regional strategies and focus on solving the problem of unbalanced and inadequate regional development by promoting development through coordination and coordination. In the implementation of major regional strategies, we should give full play to the role of effective government and effective market, promote the establishment of a reasonable industrial division and cooperation system based on comparative advantages between regions, and enhance the production economy between regions