Enterprises are the core subjects of the national innovation system and the main organizers and participants of scientific and technological innovation activities; Strengthening the leading role of enterprises in innovation and the leading role of science and technology enterprises in innovation, and further stimulating the innovation vitality of enterprises are the core foundation for comprehensively improving the efficiency of the national innovation system and accelerating the construction of a future-oriented world science and technology power. Since the 18th National Congress of the Communist Party of China, China has deeply implemented the innovation-driven development strategy, unswervingly followed the path of independent innovation with Chinese characteristics, accelerated the construction of a powerful country in science and technology, and made historic breakthroughs in promoting the construction of an innovative country with unprecedented strength. According to the Global Innovation Index (GII), in 2021, China's comprehensive ranking of national innovation strength surpassed Japan, Israel, Canada and other technologically developed countries, ranking 12th in the world, up 22 from a decade ago, and becoming the first developing country to rank among the top 15 in the world. Shenzhen - Hong Kong - Guangzhou and Beijing are the second and third technological innovation clusters in the world. The R&D investment of the whole society has increased from 1.03 trillion yuan in 2012 to 2.79 trillion yuan in 2021, ranking second in the world. In addition, China's basic research investment continues to increase. The basic research investment in 2021 is 3.4 times that in 2012, accounting for more than 6% of the R&D investment for the first time in 2021, reaching the historical peak of 6.09%, and the contribution rate of scientific and technological progress exceeds 60%. As the core subject of the national innovation system, with the continuous improvement of institutional innovation and innovation environment, the innovation vitality and innovation ability of enterprises have also been greatly improved, and enterprises have increasingly become an important subject of China's economic development, innovation input, innovation output and participation in international competition. For example, China's market entities will exceed 150 million by the end of 2021 and 160 million by June 2022. The average annual growth rate of enterprise entities will exceed 15% from 2012 to 2021. The proportion of R&D investment of Chinese enterprises in the total social R&D investment continues to rise, reaching 76.9% by 2021. The number of enterprise patent applications and authorizations accounts for more than 60% of the total number of domestic patent applications and authorizations. Huawei, OPPO, BOE and other innovative leading enterprises with the world's top 10 PCT patent applications have emerged; The number of Chinese enterprises on the Fortune Global 500 list has increased to 145, ranking first in the world for three consecutive years; Among the 50 most innovative companies in the world in 2021 released by Boston Consulting Group, 5 Chinese enterprises were selected, second only to the United States; The vitality and competitiveness of small and medium-sized enterprises and start-ups continue to improve. As of February 2022, there are more than 300 unicorn companies valued at more than US $1 billion in China, second only to the United States. Among the 40 unicorn companies with the highest valuation in the world in 2021, there are 10 unicorn companies in China, second only to the United States. The construction of a powerful country in science and technology puts forward new requirements for strengthening the dominant position of enterprises. The report of the 18th National Congress of the Communist Party of China proposed that we should accelerate the construction of the national innovation system, focus on building a technological innovation system with enterprises as the main body, market as the guidance, and the combination of industry, education and research, and highlight the need to improve