Since January 8, COVID-19 infection has officially implemented "Class B and Class B management". The focus of epidemic prevention and control has shifted from "infection prevention" to "health protection and severe disease prevention", and from risk areas and personnel management to health services and management. According to the relevant requirements of "Class B and Class B management" and the optimization and adjustment of prevention and control measures, the joint prevention and control mechanism of the State Council and the relevant departments issued the tenth version of the prevention and control plan and the tenth version of the diagnosis and treatment plan. The tenth edition of the prevention and control plan and the tenth edition of the diagnosis and treatment plan are intended to guide all regions to do a good job in epidemic prevention and control and medical treatment based on the current infection situation, effectively maintain the health and safety of the people, and ensure a smooth and orderly transition. In the past three years, in the competition with different mutant strains, China's prevention and control measures have always been studying, preventing and controlling, taking small steps and never stopping. On the day of the official implementation of "Class B and Class B control" of COVID-19 infection, all parts of the country also adjusted various prevention and control rules in accordance with the previous spirit of the Central Committee, actively created convenience for people's daily life, and worked hard to restore the original order of economic and social production and life. The entry and exit are no longer restricted, the flow of domestic people is smooth again, the dining hall food is restored in succession, and the fireworks are coming back... The bustling New Year atmosphere fills everyone's heart. The official implementation of the policy of "Class B and Class B management" for COVID-19 infection also puts forward higher requirements for the coping ability of China's medical system. Replenishing the strength of primary medical personnel, strengthening the reserve of various drugs, especially small molecule specific drugs, improving the handling capacity of fever clinics and primary medical institutions for COVID-19 infection, and strengthening the promotion of vaccination will be the key directions for attention in the future. In the long run, further improving the drug and vaccine research and development system and establishing a multi-point trigger dynamic monitoring and early warning system are related to the upgrading of China's public health capacity, and are also the work goal of complementing the current weaknesses. Of course, the reduction of COVID-19 infection to "Class B and Class B" does not mean laissez faire. COVID-19 infection is still an infectious disease, and special emergencies such as strain variation may still occur. To this end, the Tenth Edition of the Prevention and Control Plan also made response measures, specifying that seven emergency prevention and control measures will be taken during the epidemic period, including comprehensive assessment, selective home-based office measures by enterprises, institutions and factories, and temporary online teaching by kindergartens, primary and secondary schools and higher education institutions. This also shows that the new plan is proactive, to maximize the health and safety of the people, and effectively coordinate epidemic prevention and control and economic and social development. (Outlook New Era)