The report of the 20th National Congress of the Communist Party of China proposed to focus on improving the resilience and safety level of the industrial chain supply chain. The 2022 Central Economic Work Conference held not long ago also pointed out that it is necessary to "focus on the key industrial chains of the manufacturing industry, identify the key core technologies and weak links of parts and components, focus on high-quality resources to jointly tackle key problems, ensure that the industrial system is autonomous, controllable, safe and reliable, and ensure the smooth circulation of the national economy". With the implementation of the new ten measures to further optimize epidemic prevention and control, China's epidemic prevention and control has entered a new stage. How to further coordinate development and safety, and strive to improve the resilience and safety level of the industrial chain supply chain are the key factors to achieve high-quality development. Combined with the current challenges faced by China's industrial chain supply chain, we should focus on the following four aspects. First, accelerate the realization of self-reliance in high level science and technology, and lay a foundation for improving the resilience and safety level of the industrial chain supply chain. Self reliance in science and technology is the foundation and security prerequisite for the resilience of the industrial chain supply chain. First, we should continue to strengthen basic research. Focusing on the "choke" problem, we will accelerate the implementation of a number of strategic, overall and forward-looking basic research science and technology projects, encourage independent innovation, highlight originality, and stimulate innovation vitality. Secondly, we should continue to improve the level of industry university research integration, strengthen the dominant position of enterprises in scientific and technological innovation, strengthen the deep integration of enterprises led industry university research, improve the level of transformation and industrialization of scientific and technological achievements, and promote the deep integration of the innovation chain, industry chain, capital chain, talent chain. Thirdly, we must further improve the scientific and technological innovation system. We will improve the new nationwide system, strengthen the national strategic scientific and technological strength, give full play to China's super large market advantages and institutional advantages, strengthen scientific and technological research in key core areas, and gather strength to win the battle against key core technologies. The second is to accelerate the development of the real economy, so as to enhance the resilience and safety level of the industrial chain supply chain. The report of the 20th National Congress of the Communist Party of China pointed out that the focus of economic development should be on the real economy. Only by promoting the steady and sound development of the real economy can we maintain the relative integrity of China's industrial chain supply chain and maintain the advantages of China's local manufacturing industry. First of all, we should adhere to the innovation drive to promote the transformation and upgrading of the real economy. We will continue to speed up the optimization and innovation of the industry in terms of technical products, industrial organization, industrial structure, etc., promote the development of strategic emerging industry integration clusters, accelerate the construction of a new generation of information technology, artificial intelligence, biotechnology and other new growth engines, and create new advantages for future development. The second is to promote the quality and efficiency of manufacturing. We will focus on implementing industrial infrastructure reconstruction projects and major technical and equipment projects, support the development of specialized and new enterprises, and promote high-end, green, and intelligent manufacturing. At the same time, the ability and level of financial services to the real economy should be improved. Focusing on the new demand for the transformation and innovative development of the real economy, we will continue to strengthen the financial supply side reform. The third is to accelerate the promotion of industrial digital upgrading, enabling the improvement of the industrial chain supply chain flexibility and security level. The extensive application and vigorous development of digital technology and digital economy in the global scope are leading a new round of industrial revolution. The digital transformation of the industry will help to further smooth the domestic and international connection of the industrial chain supply chain, and enhance the ability to deal with uncertainty risks. First of all, we should accelerate the construction of industrial Internet and improve the level of industrial digitalization