With the continuous optimization and adjustment of epidemic prevention and control measures and the addition of factors such as the high incidence of respiratory diseases in winter, some drugs, including ibuprofen, have been in short supply for some time. Over the past few days, the reporter of Economic Information Daily has visited many places and learned that many pharmaceutical manufacturers have doubled their orders recently, and their sales have increased significantly. They have all opened up full power to expand production and guarantee supply, helping the front-line fight against the epidemic. The interviewees believe that the key to meeting epidemic prevention needs is to get through all links of the whole chain from drug production approval to raw material production, finished product distribution and market sales as soon as possible, strengthen raw material reserves and ensure smooth logistics. Rapid increase in demand Pharmaceutical enterprises urgently expanded production With the sharp increase in market demand for antipyretics, cough medicines, antibiotics, antivirals and other drugs, the reporter visited many pharmacies and learned that some antipyretics and cold medicines were out of stock, and the local pharmaceutical enterprises were operating at full capacity. In Harbin, Heilongjiang Province, the production workshop of Heilongjiang Zhenbaodao Pharmaceutical Co., Ltd. is busy. The compound Qinlan oral liquid and Shuanghuanglian oral liquid produced by the company were listed in the relevant recommended drugs. The company has launched a multi-level response mechanism for production, after-sales, inventory, distribution, etc., to achieve 24-hour uninterrupted full load production, and give priority to ensuring sufficient quantities in key areas. The sixth pharmaceutical factory of Harbin Pharmaceutical Group stepped up the production of ibuprofen granules and paediatric paracetamol huang namin granules, expanding the production lines from three to six, with the daily output exceeding 100000 boxes. Liaoning Fangda Group Northeast Pharmaceutical has a shortage of orders for paracetamol tablets, and several production lines such as paracetamol tablets, compound paracetamol and amantadine tablets, and vitamin C tablets are operating around the clock. "Now the daily output of some products can reach twice the usual level," said Gao Tiemin, deputy director of the 101 branch of the company. Shandong Xinhua Pharmaceutical Co., Ltd. is a major manufacturer of ibuprofen APIs in China. The reporter saw in their logistics warehouse center that ibuprofen tablets, ibuprofen pseudoephedrine tablets, compound licorice tablets and other medicines were stored neatly and the shipment was busy. "In the 202xy workshop, we started two production lines in an emergency, and more than 100 employees worked in three shifts without stopping work 24 hours a day," said Kou Zuxing, vice general manager of the company. In the production workshop of Jilin Aodong Yanbian Pharmaceutical Co., Ltd., 16 epidemic related drug production lines operate at full capacity and can produce 3 million pieces of oral liquid, 1.2 million bags of granules, 250000 pairs of traditional Chinese medicine prescriptions and 1.5 million tablets every day. "The production orders of Shengmai Drink, Buzhong Yiqi Pill and Shenling Baishu Powder have soared, and the orders have been filled in the first quarter of next year. We urgently transferred some logistics personnel to the front-line production," said Xia Guofeng, the company's deputy general manager of production. In the production workshop of Xinqikang Pharmaceutical Co., Ltd. located in Urumqi, Xinjiang, workers packed and boxed medicines. Chen Jincheng, the chairman of the company, said that the company had adjusted the production shift, and the output of Zukamu granules, a drug in short supply, had risen three times to the normal production period, with a daily output of 80000 boxes. On December 18, in the production workshop of Xinxiang Xinhui Pharmaceutical Co., Ltd. in Henan, the automatic bottle washing and drying procedure and filling procedure were carried out normally. Hao Xiaojie, the quality director of the company, told the reporter that with the increase of orders for antipyretic and detoxicating oral liquid, rabdosia syrup and other drugs, the person in charge of the company went to Shanghai to order packaging linkage line equipment to achieve cartoning