As a sudden respiratory virus, COVID-19 epidemic infection has brought serious harm to economic and social development. In the past three years, COVID-19 has constantly mutated, posing new challenges to epidemic prevention and control. Combined with the practice and data analysis of epidemic prevention and control at home and abroad, the Omikjon virus strain is highly infectious, and the severe incidence rate and mortality are reduced. In the last month, the state introduced a series of policies and measures, which are of great significance for effective prevention and control of the COVID-19 epidemic. How to avoid virus infection and effectively improve the quality of epidemic prevention has become the focus of widespread concern. We believe that to further play the role of traditional Chinese medicine in prevention and treatment, effectively reduce the rate of coronavirus infection, improve clinical symptoms, and improve the cure rate is still one of the key tasks of preventing and controlling COVID-19 infection. It is the responsibility and mission of our medical and health industry to attach great importance to and deeply understand the long-term and complexity of various viruses and bacteria, and scientifically grasp the onset characteristics, evolution characteristics and prevention and control laws of sudden epidemic infectious diseases. China's five thousand year history of civilization is a process of constant struggle against epidemics. From the Western Zhou Dynasty to the end of the Qing Dynasty and the Republic of China, there were more than 500 pandemics, and basically new epidemics occurred in a few years. The epidemic was characterized by "five plagues are easy to catch", and the degree of illness even "every family has the pain of zombies, and every room has the grief of wailing". It is precisely the continuous practice and innovation of the theories and methods of traditional Chinese medicine, such as the syndrome differentiation of the six meridians of typhoid fever, the syndrome differentiation of the warm disease, the syndrome differentiation of the three energizers, and the syndrome differentiation of the plague from the exterior to the interior, which effectively guides the Chinese people in epidemic prevention and treatment, and protects the prosperity of the Chinese nation. Since the outbreak of the COVID-19, the recent five editions of the COVID-19 Prevention and Control Plan have defined the methods of traditional Chinese medicine prevention and treatment, and the clinical promotion and application of three ways and three medicines. Traditional Chinese medicine has played a certain role in preventing and controlling the COVID-19. However, the dominant role of traditional Chinese medicine in the prevention and treatment of epidemic diseases still needs to be fully played, especially in the prevention of COVID-19 infection, which needs to be widely recognized by the society. Comprehensively raising the awareness of the importance and necessity of epidemic prevention of traditional Chinese medicine, effectively avoiding the tendency of "demonizing coronavirus" and "weakening traditional Chinese medicine", and further giving play to the role of traditional Chinese medicine in preventing and controlling COVID-19 infection can improve the ability of prevention and control of COVID-19 infection, improve the public's ability to take initiative in epidemic prevention and maintain health, so as to effectively reduce the losses caused by the epidemic to people, society and the country. First, efforts should be made to prevent virus infection. With the constant variation of the Omicron virus strain, its mortality and severity rate have decreased, but its infectivity has increased and the number of infected people has increased, so it is necessary to take the initiative to prevent it. Chinese medicine focuses on the following three aspects to prevent epidemics. First, avoid poison. The Yellow Emperor's Canon of Internal Medicine emphasizes that "to avoid its poisonous gas, the female will never die". The nose is the orifice of the lung, the passage for gas to enter and exit, and the main way for the gas of plague to invade the human body. The Plague Theory: The Original Disease said: "The breath of ordinary people is connected with the weather... This breath is just the right time to be in debt, and in the process of breathing, external evils can take advantage of it." Therefore, wearing masks, keeping social distance and preventing viruses from entering through the nose and mouth are effective ways to prevent epidemics. It is recorded in the Forbidden Prescription compiled by Chuanya Internally and Internally: "Anyone who enters a plague home, smears sesame oil into his nostrils, and then goes to the sick home, will not be infected." Also can use realgar, ferula and other traditional Chinese medicine powder stuffed in the nasal cavity to avoid poison. The Medical Prescription Examination - Plague Gate points out: "Fanjue