Animal cells may also have the same photosynthesis as plants, and the "door of time" to reverse cell degeneration and aging has been opened. On December 8, Beijing time, the original scientific research achievements of Run Run Shaw Hospital affiliated to Zhejiang University School of Medicine were published in the international journal Nature in the form of a long article, becoming the first orthopedic research article published in Nature in China. The team of Lin Xianfeng, a physician and Professor Fan Shunwu from the Department of Orthopaedics of Run Run Run Shaw Hospital affiliated to Zhejiang University Medical College, and Tang Ruikang, a professor from the Department of Chemistry of Zhejiang University, successfully extracted the "biological battery" with photosynthesis - thylakoid from spinach, and for the first time in the world, the plant thylakoid was delivered across species to the cells of animal aging lesions, so that animal cells also have the energy of plant photosynthesis. For billions of years, thylakoid has become an almost perfect energy supplying organelle evolved by plants, and is an energy factory that can generate ATP (adenine nucleoside triphosphate) and NADPH (reductive coenzyme II) in a controlled and stable manner. More and more studies have found that the energy shortage of animal cells is the key reason for the occurrence and development of tissue aging and degenerative diseases. ATP and NADPH are indispensable energy currency and material currency for cell regeneration and repair. Through interdisciplinary technical means, the research team has systematically verified that the nano thylakoid encapsulated by chondrocyte membrane can not only effectively escape the elimination of the immune system, but also be selectively ingested by degenerated chondrocytes after more than a year of experiments and test analysis. Through non-invasive light therapy in vitro, the level of ATP and NADPH in degenerated chondrocytes can be precisely enhanced and sufficient "endurance" can be maintained, so as to reshape the anabolism of chondrocytes and achieve the treatment of degenerative osteoarthritis and other diseases. George Caputa, editor of Nature magazine, commented: "How to deliver energy to cells has always been a huge problem in cell biology and clinical medicine, and the correct supply of specific metabolite content is a lasting challenge in clinical treatment. What better way to solve the above problem than to deliver thylakoids, a factory that has undergone billions of years of life evolution?" The paper reviewer Francisco Cejudo said: "The outstanding point of this work is that the research team has successfully transplanted plant 'micro organelles' into mammalian cells. The technology of using plant photosynthesis system to specifically supply ATP and NADPH in mammalian cells in a light energy dependent manner is an exciting achievement, which opens up the possibility of metabolic engineering." It is reported that in the same period, the "Research briefing" column of Nature published the article "Plant cell devices realize the transfer of metabolites to mammalian cells", which publicized and reported and positively evaluated the research results. At present, the research team has simultaneously submitted invention patents and started product transformation. (Outlook New Times)