"We have just completed the declaration for the identification of the national silkworm genetic resource gene bank." On December 1, Professor Dai Fangyin, the director of the State Key Laboratory of Silkworm Genome Biology of Southwest University and the chief scientist of the technical system of the national silkworm industry, who was busy in the laboratory, said that they would further strengthen the research foundation and support of silkworm genetic resources on the basis of building the world's largest silkworm gene bank in the early stage. As the only national key laboratory in the field of sericulture in China, the State Key Laboratory of Silkworm Genome Biology has successively released several important achievements this year. Complete the "1000 silkworm genome project" of germplasm resources, release the world's first "super pan genome map of silkworm", take the lead in creating the "digital silkworm" gene bank, and promote China's silkworm research to the stage of molecular design breeding; Complete the "Single cell Transcription Histogram of Silkworm Silk Producing Organs", and achieve the single-cell level of silk gland research. "The report of the Twentieth National Congress of the Communist Party of China pointed out that we should speed up the realization of high-level science and technology for self-reliance. Our laboratory has given full play to the advantages of organized scientific research, and successfully led China's sericulture science and technology to become the world leader in the overall construction of 11 years. We will take practical actions to realize the commitment of scientific and technological innovation to support the high-quality development of modern sericulture industry." Dai Fangyin said that after the release of the silkworm super pan gene map, they had become more urgent in their research work. The team accelerated the systematic excavation and related expansion research of the silkworm pan genome, and started the new era innovation project of "transforming the silkworm and making multiple use of it". If the traditional "Silk Road" is mainly an industry based on silk products trade, the "New Silk Road" in the 21st century will focus on modern science and technology such as genome research, improve the scientific and technological content of sericulture silk and its derivatives development, and find and build a breakthrough road of modern sericulture industry. The recently released "Silkworm Super Pan Genome Map" was completed by the Dai Fang Yintuan team over four years. They have conducted in-depth sequencing of 1078 silkworm germplasm resources, including the most comprehensive genome information of silkworm and wild mulberry silkworm, which is the largest long reading and long pan genome in the world's animals and plants, and also the highest quality silkworm genome map. "The completion of silkworm super pan genome will break through its breeding bottleneck and open a new era of molecular breeding." Xiang Zhonghuai, an academician of the CAE Member, said that previously identifying genes for specific traits or their causal variations was like "looking for a needle in a haystack", but now it can be called "catching a turtle in a jar", because the completion of pan genome can greatly improve the efficiency of mining excellent breeding genes. On this basis, we can achieve design breeding based on breeding goals, combined with molecular breeding methods such as genome selection, gene editing, synthetic biology, etc. Build a cross innovation team based on the "sericulture+" model to "establish a mulberry industry and develop in a diversified way" In recent years, the laboratory has taken the opportunity of optimization and reorganization of national key laboratories, focused on strengthening the basic frontier and key technology innovation of the industrial chain, and built a cross innovation team with the "sericulture+" model. The original innovation ability has been significantly improved. The development of sericulture science is being integrated into big science, big agriculture, big textile, big people's livelihood, and big consumption... "This is Xiang Zhonghuai, the laboratory and the academic leader of sericulture in China