People buy medicine online, what can they buy and what can't? How to buy prescription drugs online? Are drug websites authentic? Is the safety supervision of drugs strict? The Measures for the Supervision and Administration of Online Drug Sales (hereinafter referred to as the Measures), which will be officially implemented on December 1, has answered the above questions. According to the Measures, vaccines, blood products, narcotic drugs, psychotropic drugs, toxic drugs for medical use, radioactive drugs, pharmaceutical precursor chemicals and other drugs under special control of the State shall not be sold on the Internet. At the same time, we will strictly manage the whole process of drug distribution, and put forward clear requirements for the quality and safety management system, pharmaceutical services, drug storage and distribution, drug traceability, risk control, information disclosure and other whole process management of drug online sales enterprises. When selling prescription drugs online, drug online retail enterprises should strictly follow the relevant regulations for prescription review and allocation. The insiders and experts interviewed by the reporter of the Rule of Law Daily pointed out that this time, the Measures revealed that the regulatory attitude tends to be strict and standardized. At the same time, it followed the principle of "online and offline consistency" in business supervision, and made more strict and specific provisions on the separate display of prescription drugs sold online, prescription before drug, and ensuring the authenticity of handling. With the formal implementation of the Measures, online drug sales will have laws and regulations to follow, and truly usher in the era of strong supervision. The potential risks of the rapid development of online drug sales cannot be ignored. In recent years, with the issuance of a series of policies such as the Opinions of the General Office of the State Council on Promoting the Development of "Internet plus+Medical Health", the Guiding Opinions of the State Council on Actively Promoting the Action of "Internet plus" and so on, "Internet+medical health" has ushered in the opportunity of rapid development, and all links of the pharmaceutical industry chain have carried out an overall layout online and offline, In addition to the improvement of third-party service supporting capabilities such as logistics distribution, the growth rate of online drug retail terminals increased significantly. According to the statistics of the Southern Institute of Pharmaceutical Economics of the State Food and Drug Administration, although the growth rate of online sales of pharmaceutical retail will slow down in 2021, it will still be the highest among the four terminals. It is estimated that the annual sales in 2022 will be 289.9 billion yuan, with a growth rate of more than 32%. The industry will continue to maintain a rapid growth. With the continuous liberalization of online sales of prescription drugs and medical insurance payment, the number of patients who buy prescription drugs online is gradually increasing. According to the sales data of more than 200 pharmacies on Tmall and JD platforms, from January to July 2022, the sales of online prescriptions reached 14.47 billion yuan, a year-on-year increase of 48.9%. However, there are some hidden risks behind the rapid development of online drug sales. The relevant person in charge of the Drug Administration of the State Food and Drug Administration pointed out that Internet sales are characterized by virtuality, concealment, divergence, and cross region. In particular, there are many types of subjects in online drug sales, different types of subjects have different risks, and different management methods, which pose challenges to supervision and management, law enforcement jurisdiction, case investigation, evidence fixation and other regulatory behaviors. Du Xiujun, a lawyer from Beijing Zhongwen Law Firm, has been concerned about online drug sales for a long time. He has noticed that at present, the information publicity and verification of sales subjects are insufficient, the regulation of prescription issuance is difficult, the regulation of online drug sales channels is difficult, the source of fake and inferior drugs is difficult to track, third-party platforms and sales enterprises