"Modern science has entered the stage of quantum mechanics and relativity, while medicine is still in the stage of classical mechanics." At the recent meeting on the development of basic medical disciplines in China, Han Qide, honorary chairman of the Chinese Association for Science and Technology and academician of the CAS Member, pointed out that due to the limitations of current human cognition of the body and disease, many medical problems are difficult to achieve fundamental breakthroughs, and basic research should strengthen scientific research from a "predictive" height. "Medicine should be fully integrated with science, engineering, social sciences and humanities." Wang Chen, president of the Chinese Academy of Medical Sciences and an academician of the CAE Member, said that the current medical science is far from enough in the use of mathematics, physics, chemistry and other disciplines, and should establish more powerful basic medical research through cross integration. Basic research is the source of scientific and technological innovation. The experts at the meeting believed that the pioneering and subversive nature of basic medical research depends on the depth and breadth of its intersection with other disciplines, and also directly determines the level of human cognition of life sciences. The report of the 20th National Congress of the Communist Party of China proposed to strengthen basic research, highlight originality and encourage free exploration. Under the new historical conditions, how should we further strengthen the strength of basic medical research in China, and then lead the development direction of medical science and technology innovation? Basic research cannot be overemphasized. "Pan Jianwei, an academician of the CAS Member, pointed out that a smartphone has more than eight Nobel Prize achievements, emphasizing the importance of basic research." Dong Erdan, a liberal chair professor of Peking University and an academician of the CAE Member, said that this is especially true in the medical field. One gene therapy also includes eight or more Nobel Prize winning achievements, such as the discovery of DNA double helix structure, DNA sequencing technology, gene editing technology, etc. Basic medicine is the source power of medical innovation, which cannot be overemphasized. Zhan Qimin, a professor at Peking University and an academician of the CAE Member, made an analogy: "Life science problems and clinical disease problems are like the tip of an iceberg exposed on the surface. Below the surface is a broader range of basic science problems. To crack them, it requires joint research in many disciplines, including chemistry, medicine, engineering, science, materials science, optics, big data, artificial intelligence, and so on." Wang Chen stressed that the basic research of modern medicine should aim at the health of people and people, and should go beyond the previously understood categories of physiology, biochemistry and life sciences. It should not only develop with natural sciences such as science and engineering, but also blend with social sciences and humanities. Strengthening basic research is an inevitable requirement for scientific and technological self-reliance. "Most of the initial patents of clinical drugs in China came from abroad, most of the large medical equipment was imported from abroad, and most of the clinical standards and guidelines were borrowed from abroad." Zhan Qimin pointed out that these practical problems just reflected the lack of support for corresponding basic research in the medical field of China. For example, if basic research is insufficient, there will be no original targets, markers, etc., and it will be difficult to develop good drugs and treatments by ourselves. Strengthening basic research is an inevitable requirement for independent development of science and technology. Liu Dengfeng, the supervisor of the Department of Science and Education of the National Health Commission, said that the basic research of original innovation should raise real problems and solve real problems. There is still much room for improvement in the current output quality. The initiative, innovation potential and creativity should be stimulated to challenge the most cutting-edge medical science problems. Base