"Self reliance and self-improvement in science and technology is the foundation of national prosperity and the key to security." This has once again sounded the "charge" for the in-depth implementation of the innovation driven development strategy and the acceleration of self-reliance and self-improvement in science and technology. If science and technology is established, the nation will be established, and if science and technology is strong, the country will be strong. Scientific and technological innovation has always been an important force to promote the development of a country and a nation. It can be said that whoever takes the initiative in the development of science and technology will grasp the opportunities for future development. In this sense, to grasp innovation, development, innovation and the future, we must rely on scientific and technological forces to transform the driving force of development and provide strategic support for improving social productivity and comprehensive national strength. Scientific and technological innovation is at the core of national development. Since the 18th National Congress of the Communist Party of China, we have comprehensively analyzed the competitive situation of international scientific and technological innovation, deeply studied and judged the development situation at home and abroad, and comprehensively planned scientific and technological innovation in view of the outstanding problems and challenges faced by China's scientific and technological undertakings. Important progress has been made in basic research and original innovation, new breakthroughs have been made in strategic high-tech fields, and remarkable achievements have been made in Minsheng science and technology, especially in the prevention and control of the COVID-19. Chang'e, Jiuzhang, Kunlong, Beidou, Tianwen, Hualong... All of these romantic names represent scientific and technological achievements that amaze the world. Through efforts, China's scientific and technological strength is moving from quantitative accumulation to qualitative leap, from point breakthrough to system capability improvement, and scientific and technological innovation has made new historic achievements. Scientific and technological competition is like sailing against the current. If you don't advance, you will fall back. It should be noted that China's original innovation ability is not strong, the overall efficiency of the innovation system is not high, the integration of scientific and technological innovation resources is not enough, the layout of scientific and technological innovation forces needs to be optimized, the efficiency of scientific and technological input and output is low, the structure of scientific and technological talents needs to be optimized, the scientific and technological evaluation system does not meet the requirements of scientific and technological development, and the scientific and Technological Ecology needs to be further improved... These problems in development are both difficult and important, We must continue to make great efforts to solve it. Facts have proved that the core technology is controlled by others is the biggest hidden danger. Only by self-reliance and mastering the core technology in our own hands can we truly take the initiative in competition and development and fundamentally ensure the national economic security, national defense security and other security. We should firmly grasp the lifeline of science and technology in our own hands, adhere to the problem orientation, and rush to the most urgent and urgent problems. It is urgent to break through the key core technology of "bottleneck". We must adhere to the problem orientation and give full play to the advantages of the new national system. It is necessary to proceed from the urgent needs and long-term needs of the country, not only in some key industries, key areas, and key core technologies, but also aim at cutting-edge fields and advanced technologies, and prospectively deploy a number of strategic and reserve technology research and development projects, aiming at the commanding heights of future science and technology and industrial development. If every city, high-tech Development Zone, science and technology enterprise and scientific research worker can promote scientific and technological innovation in a down-to-earth manner around the development direction determined by the state, we will certainly be able to achieve the set goals. Scientific and technological innovation depends on investment and talents. In the final analysis, scientific and technological competition is a competition for talents, and cultivating innovative talents is also a major plan for the long-term development of the country and the nation. In the past, we adhered to talent driven, constantly improved the talent development environment, stimulated talent creativity, and vigorously cultivated a large number of strategic scientific and technological talents, leading scientific and technological talents, young scientific and technological talents and high-level innovation teams with a global vision and international level. To solve new problems and meet new challenges, we should strive to cultivate a group of top scientific and technological talents with world influence, stably support a group of innovative teams, cultivate more high-quality technical talents, skilled craftsmen and craftsmen from large countries, and develop and make good use of both international and domestic human resources, so as to gather talents from all over the world and use them. We will open up a wide range of ways to become talents, make good use of talents regardless of their style, and let the innovative wisdom of all kinds of talents burst forth. We will certainly be able to promote scientific and technological innovation. Today, we are closer to the goal of the great rejuvenation of the Chinese nation than at any time in history. To achieve this goal, we must unswervingly follow the road of strengthening the country through science and technology. Working hard, catching up, constantly improving the independence, autonomy and security of China's development, giving birth to more new technologies and new industries, will certainly open up new fields and new tracks for economic development, form new international competitive advantages, and help build China into a world power in science and technology. (outlook new era)