Today, the 20th academician conference of the Chinese Academy of Sciences, the 15th academician conference of the Chinese Academy of engineering and the 10th National Congress of the China Association for science and technology opened ceremoniously. This is an important moment for us to discuss the grand plan of promoting China's scientific and technological innovation and development at the historical intersection of the "two centenary" goals and opening a new journey of building a modern socialist country in an all-round way. First of all, on behalf of the Party Central Committee, I would like to extend my warm congratulations on the convening of the conference! Extend sincere condolences to the scientific and technological workers who have worked hard in various posts! May 30 is the Fifth National Science and technology workers' day. I extend holiday greetings to the majority of science and technology workers all over the country! This year marks the centenary of the founding of the Communist Party of China. In the historical periods of revolution, construction and reform, our Party attaches great importance to the cause of science and technology. From attaching great importance to the work of intellectuals during the revolutionary period, to sounding the horn of "marching towards science" after the founding of new China, to the proposition that "science and technology is the first productive force" put forward by reform and opening up; From the in-depth implementation of the knowledge innovation project, the strategy of rejuvenating the country through science and education and the strategy of strengthening the country through talents in the new century, the continuous improvement of the national innovation system and the construction of an innovative country, to the proposal that innovation is the first driving force after the 18th CPC National Congress, the full implementation of the innovation driven development strategy and the construction of a world scientific and technological power, science and technology has always played a very important strategic position and played a very important strategic role in the cause of the party and the people. Since the 19th CPC National Congress, the CPC Central Committee has comprehensively analyzed the competition situation of international scientific and technological innovation, deeply studied and judged the development situation at home and abroad, adhered to placing scientific and technological innovation at the core of the overall national development situation and comprehensively planned scientific and technological innovation in view of the outstanding problems and challenges faced by China's scientific and technological cause. We adhere to the party's overall leadership over the cause of science and technology, look at the overall situation, grasp the root, and form an efficient organization and mobilization system and an overall and coordinated allocation mode of scientific and technological resources. We firmly grasp the strategic goal of building a world power in science and technology, seize the opportunity of global scientific and technological development with the sense of mission, responsibility and urgency of seizing the day, and strive to be the first in the basic frontier fields. We give full play to the leading role of scientific and technological innovation, strive to make new breakthroughs in original innovation, achieve leapfrog development in important scientific and technological fields, promote the independent control of key core technologies, and strengthen the integration of innovation chain and industrial chain. We have comprehensively deployed the reform of the scientific and technological innovation system and introduced a series of major reform measures to improve the overall efficiency of the national innovation system. We strive to implement the strategy of strengthening the country with talents, create a good ecological environment for talent innovation, gather talents from all over the world, and fully stimulate the enthusiasm, initiative and creativity of the majority of scientific and technological personnel. We will expand openness and cooperation in the field of science and technology, actively integrate into the global network of scientific and technological innovation, actively participate in solving the major challenges facing mankind, and strive to promote the benefits of scientific and technological innovation to more countries and people. In 2016, we held the National Conference on scientific and technological innovation, the conference of academicians of the two academies and the Ninth National Congress of the China Association for science and technology. In 2018, we held the conference of academicians of the two academies. Over the past few years, under the strong leadership of the Party Central Committee and with the joint efforts of the national scientific and technological circles and all sectors of society, China's scientific and technological strength is moving from quantitative accumulation to qualitative leap, from point breakthrough to system capability improvement, and scientific and technological innovation has made new historic achievements. —— Important progress has been made in basic research and original innovation. The overall strength of basic research has been significantly strengthened, and the overall level of chemistry, materials, physics, engineering and other disciplines has been significantly improved. We have made a number of major original achievements in frontier directions such as quantum information, stem cells and brain science. Successfully organized a number of major basic research missions, "chang'e-5" realized the sampling and return of extraterrestrial objects, "tianwen-1" started the exploration of Mars, "huairou-1" gravity wave storm high-energy electromagnetic counterpart all day monitor satellite was successfully launched, "Huiyan" directly measured the strongest magnetic field in the universe so far, the 500 meter aperture spherical radio telescope found millisecond pulsars for the first time, and the new generation of "artificial sun" was discharged for the first time, "Xuelong 2" made its maiden voyage to the South Pole. The 76 photon quantum computing prototype "Chapter 9" and the 62 bit programmable superconducting quantum computing prototype "Zuchongzhi" were successfully launched. A number of major scientific and technological infrastructure with world-class level, such as spallation neutron source, have passed the acceptance. —— New leaps have been made in the field of strategic high technology. Actively seize the commanding heights of science and technology in the fields of deep sea, deep space, deep earth and deep blue. "Haidou-1" completed the 10000 meter sea trial, the "striver" successfully sat on the bottom, the Beidou satellite navigation system was fully opened, the Tianhe core module of the Chinese space station was successfully launched, the "long March-5" remote-3 carrier rocket was successfully launched, the world's strongest deep-seated nuclear astrophysics accelerator was successfully launched, and the "Shenwei Taihu Lake light" supercomputer realized the parallel first principle calculation and Simulation of tens of millions of cores for the first time, Mozi realizes relay free thousand kilometer quantum key distribution. The first trial voyage of "Tiankun" was successful. New breakthroughs have been made in the third generation nuclear power technology of "guohe-1" and "hualong-1". —— New breakthroughs have been made in high-end industries. The shield has successfully launched at a maximum speed of 919 kilometers per hour, and the shield has been successfully prepared for the test run of the large-diameter maglev aircraft. Beijing Daxing International Airport was officially put into operation, and the Hong Kong Zhuhai Macao Bridge was put into operation. Intelligent manufacturing has made great progress, artificial intelligence and digital economy are booming, image recognition and speech recognition are at the forefront of the world, and 5g mobile communication technology is the first to realize large-scale application. The development of new energy vehicles was accelerated. Consumer UAVs account for more than half of the global market. The continuous innovation of methanol to olefin technology has driven the rapid development of China's coal to olefin industry. —— Science and technology have played an important role in the prevention and control of COVID-19. The scientific and technological circles have provided scientific and technological support and decision-making support for the party and the government to deal with the epidemic scientifically. The world's first novel coronavirus strain was successfully isolated, the virus genome was sequenced, a batch of clinical treatment drugs, testing equipment and reagents were developed, and a variety of vaccines were developed and applied. Science and technology provided strong support in the control of infection, virus traceability, disease treatment, vaccine and drug research and development, resumption of work and production, and played a successful scientific and technological anti epidemic war. —— Remarkable achievements have been made in the field of people's Livelihood Science and technology. Significant progress has been made in the localization and substitution of high-end medical equipment such as medical heavy ion accelerator, magnetic resonance, color Doppler ultrasound and CT. Using scientific and technological means to build a new model of targeted poverty alleviation, cultivate scientific and technological industries and scientific and technological talents for poor areas. Science and technology has played an important role in winning the battle against poverty. The promotion and application of a number of key technologies such as clean and efficient combustion of coal and ultra-low emission control of multi pollutants from steel have promoted the improvement of air quality. —— Major achievements have been made in national defense science and technology innovation. National Defense Science and technology strongly supported the research and development of major weapons and equipment. The first domestic aircraft carrier was launched and the fifth generation fighter j-20 was officially put into service. With the successful development of dongfeng-17 ballistic missile, China is in the forefront of hypersonic weapons. Practice has proved that China's independent innovation is promising! The vast number of scientific and technological workers in China have made great achievements! With the spirit of keeping pace with the times, the courage of innovation and perseverance, the majority of scientific and technological workers in China should face the world's scientific and technological frontier, the main economic battlefield, the major needs of the country and the people's life and health, grasp the general trend, seize the opportunity, face the problems, face the difficulties, shoulder the important task entrusted by the times, and strive to achieve high-level scientific and technological self-reliance and self-improvement! Fellow academicians, comrades and friends! In today's world, the great changes not seen in a century have accelerated the evolution, the international environment is complex, the world economy is in a downturn, the global industrial chain and supply chain are facing reconstruction, and the instability and uncertainty have increased significantly. The COVID-19 has a wide and far-reaching impact, and the ideological trend of anti globalization, unilateralism and protectionism is surging. Scientific and technological innovation has become the main battlefield of international strategic game, and the competition around the commanding height of science and technology is unprecedented fierce. We must maintain a strong sense of hardship and make full ideological and work preparations. At present, the new round of scientific and technological revolution and industrial reform are advancing by leaps and bounds, the scientific research paradigm is undergoing profound changes, the interdisciplinary integration is developing, and the penetration and integration of science and technology and economic and social development is accelerating. The breadth of scientific and technological innovation has increased significantly. The macro world, ranging from the operation of celestial bodies, Galaxy Evolution and the origin of the universe, to the micro world, ranging from gene editing, particle structure and quantum control, is the forefront of scientific and Technological Development in the world. The depth of scientific and technological innovation has been significantly deepened. Deep space exploration has become the commanding height of scientific and technological competition. Deep sea and deep earth exploration continue to expand new horizons for human understanding of nature. The speed of scientific and technological innovation has accelerated significantly. The rapid development of emerging technologies represented by information technology and artificial intelligence has greatly expanded the scope of time, space and people's cognition. Mankind is entering an era of intelligent interconnection of all things with the ternary integration of "man-machine and object". Basic research and applied research in bioscience have developed rapidly. The precision of scientific and technological innovation has been significantly enhanced, and the research on biological macromolecules and genes has entered the stage of precise regulation. From understanding and transforming life to synthetic life and designing life, it not only brings benefits to mankind, but also brings bioethical challenges. After years of efforts, the overall level of science and technology in China has been greatly improved. We have the foundation, confidence, confidence and ability to seize the opportunity of a new round of scientific and technological revolution and industrial reform, seize the momentum and expand our grand plans. At the same time, we should also see that China's original innovation ability is not strong, the overall efficiency of the innovation system is not high, the integration of scientific and technological innovation resources is not enough, the layout of scientific and technological innovation forces needs to be optimized, the efficiency of scientific and technological input-output is low, the structure of scientific and technological talents needs to be optimized, the scientific and technological evaluation system does not meet the requirements of scientific and technological development, and the scientific and Technological Ecology needs to be further improved. Many of these problems are long-standing difficulties that need to be solved with great efforts. The 19th National Congress of the Communist Party of China established the strategic goal of becoming an innovative country by 2035. The Fifth Plenary Session of the 19th CPC Central Committee proposed to adhere to the core position of innovation in the overall situation of China's modernization and take the self-reliance and self-improvement of science and technology as the strategic support for national development. Based on the new development stage, implementing the new development concept, building a new development pattern and promoting high-quality development, we must deeply implement the strategy of rejuvenating the country through science and education, the strategy of strengthening the country with talents and the strategy of innovation driven development, improve the national innovation system, speed up the construction of a strong country in science and technology and achieve high-level scientific and technological self-reliance and self-improvement. First, strengthen the original and leading scientific and technological research, and resolutely win the battle of key core technologies. If science and technology is established, the nation will be established, and if science and technology is strong, the country will be strong. Strengthening basic research is an inevitable requirement for the self-reliance of science and technology, and an inevitable choice for us from unknown to known and from uncertainty to certainty. We should speed up the formulation of a ten-year action plan for basic research. Basic research should dare to explore and highlight originality, promote the exploration and discovery of the evolution of the universe, the essence of consciousness, material structure and the origin of life, expand the boundary of understanding nature and open up new cognitive territory. Basic research should apply traction and break through bottlenecks, refine scientific problems from the practical problems faced by economic and social development and national security, and understand the basic theory and technical principle of "neck" technology. We should increase financial investment in basic research, optimize the expenditure structure, implement tax incentives for enterprises' investment in basic research, and encourage society