From an unknown border town to an international metropolis with global influence, Shenzhen is a brand-new city created by the party and the people after the reform and opening up. It is a wonderful interpretation of socialism with Chinese characteristics on a piece of white paper. On August 18, 2019, the opinions of the CPC Central Committee and the State Council on supporting the construction of a leading demonstration zone of socialism with Chinese characteristics in Shenzhen (hereinafter referred to as the "opinions") was officially released, opening the historical curtain of the construction of a leading demonstration zone in Shenzhen. Since the issuance of the opinions, the Central Committee, the provincial Party committee and the provincial government have given careful guidance and strong support to Shenzhen. Shenzhen has kept in mind its entrustment, made progress with gratitude and made every effort to promote the implementation of various tasks. Up to now, of the 56 key tasks put forward in the opinions of the CPC Central Committee and the State Council on supporting the construction of Shenzhen's leading demonstration zone, 11 have been completed, including the exploration of intellectual property securitization, 45 have made significant progress, 47 experience and practices in five aspects have been popularized throughout the country, and the leading demonstration role of Shenzhen has been further highlighted. Keep a distant mind and do solid work. This international innovative city full of charm, power, vitality and innovation is becoming a wonderful model of socialism with Chinese characteristics in the new era, showing the world the great power of China's reform and opening up and the bright prospect of socialism with Chinese characteristics. High quality development is at the forefront of the country According to the work report of Shenzhen Municipal Government in 2022 released on April 11, Shenzhen's GDP reached 3.07 trillion yuan in 2021, with a year-on-year increase of 6.7%. In the past five years, Shenzhen's GDP has steadily stood at a new level of 3 trillion yuan from 2 trillion yuan. After Shanghai (2017) and Beijing (2018), Shenzhen has become the third city with a regional GDP exceeding 3 trillion yuan in China. Firmly implement the new development concept and spare no effort to build a high-quality development highland. In recent years, Shenzhen has insisted that development is the first priority, talents are the first resource and innovation is the first driving force, promoted the historic transformation and systematic reconstruction of the innovation system, and gradually established the whole process innovation ecological chain of "basic research + technological breakthrough + industrialization of achievements + science, technology and Finance + talent support". The construction of a comprehensive national science center has been continuously promoted, and a number of original innovation sources such as Pengcheng laboratory, Guangming Science City and Hetao Shenzhen Hong Kong scientific and technological innovation cooperation zone have been accelerated... In the past few years, Shenzhen's basic research capacity has been steadily improved. At present, the proportion of social R & D investment in Shenzhen in GDP has exceeded 5%, ranking in the forefront of large and medium-sized cities in China. Through the legislation of the special zone, Shenzhen made it clear that the government's investment in basic research and applied basic research should not be less than 30% of the Municipal Science and technology R & D funds, and took the lead in forming a long-term, sustained and stable investment mechanism for basic research. In the past few years, Shenzhen's industrial structure has been continuously optimized. The total output value of industries above designated size has ranked first in China for three consecutive years. The added value of strategic emerging industries accounts for 39.6% of GDP and ranks first in large and medium-sized cities in China. The added value of modern service industry has increased to 76.5% of the added value of service industry. By implementing the "chain leader system" of key industries and creating a "matrix" industrial support system, Shenzhen promotes the establishment of an industrial ecology of "leading geese to fly", speeds up the integration of "four chains" of industrial chain, innovation chain, talent chain and education chain, and constructs a modern industrial system facing the future. At present, there are more than 18600 national high-tech enterprises in the city, and the banner of high-tech industry development is held higher and more stable. Gather talents from all over the world and use them. Shenzhen focuses on talent development and does not relax. Shenzhen insists on taking talent leading development as the core strategy of urban development, establishes talent day and entrepreneur day, systematically restructures and optimizes the talent policy system, and focuses on strengthening talent support. Shenzhen is like a magnet, attracting all kinds of excellent talents to accelerate the gathering. According to the latest data, there are 74 full-time academicians gathered in Shenzhen, with more than 5000 postdoctors, more than 2 million scientific and technological talents, and a total of 6 million talents. The whole people jointly write the answer sheet of model civilization "I'm really glad to spend this memorable time with you..." this is a thank-you letter from Shenzhen volunteer Yang Dong to two cats. On April 7, Xiaohe, a resident of Yan village, shangshatang, Futian District, was released from isolation and took back his pet. On the same day, 24 representatives including Zhu Keding, deputy to the Shenzhen Municipal People's Congress, jointly submitted a proposal on setting up a pet health post station during the epidemic. During the epidemic, two temporary pet love post stations in Shenzhen took in more than 260 pets free of charge. The first "pet shelter hospital" explores the way for the whole country. Volunteers and pets heal each other and warm people's hearts. A civilization concerto is sung in Pengcheng. Recently, the Central Civilization Office announced the annual evaluation results of national civilized cities in 2021. Shenzhen ranked second among the 30 provincial capitals and sub provincial civilized cities in China, and has been awarded the title of "national civilized city" for seven consecutive years. The answer of urban civilization is not only in the back streets and alleys, farmers' markets, Wucun communities, but also in the hearts of every resident. The responsibility of "call me", the temporary residence of the express brother and the timely solution to the dilemma of Nanshan breakfast shop are not to ignore the voice of each "individual"; The citizen carried the quilt to catch the girl who fell from the building, the stewardess saved the elderly with cardiac arrest by three rounds of CPR, and more than 20 passers-by carried the car to save the pressed boy, which is the feedback of ordinary people to the whole city. Love is surging here. Up to now, the number of registered volunteers in Shenzhen has exceeded 2.6 million, accounting for 15.3% of the permanent population. Shenzhen has become a "city of volunteers" and "giving roses has fragrance in hands" has become a city motto. Civilization is rooted here. At present, there are 50 new era civilization practice institutes and 438 new era civilization practice stations in Shenzhen, which have become the positions for standardization, mechanism construction and normalization of mass publicity and education activities and voluntary service activities. "The sky pump in zone T1 can start to work. Move!" "Received, received!" As the temperature gets warmer, the reconstruction and upgrading project of Shenzhen sports center is in full swing. This is a silhouette of Shenzhen vigorously promoting the construction of cultural and sports facilities since the 13th five year plan. During the period of "opening the top ten districts of Shenzhen music and art academy", the "top ten districts of Shenzhen music and art academy" will be fully upgraded, and the "top ten districts of Shenzhen music and art academy" will be put into operation in turn; More than 1000 parks of various types have been built, and new cultural spaces such as "Nanshan study" and Yantian meet library have appeared one after another. The large-scale Symphony suite "my motherland" and dance "eternal life in the fire" have been selected into the "stage art boutique creation project celebrating the 100th anniversary of the founding of the Communist Party of China" - a panoramic view of the civilization transcript. While the "hard investment" of people's livelihood, Shenzhen also has a "soft guarantee" of civilization. In July 2020, Shenzhen Municipal Commission of civilization issued the implementation plan of Shenzhen for strengthening citizen moral construction in the new era, raising civilization to the level of rule of law. Electric vehicle riders do not wear helmets, run red lights and go retrograde; Failing to classify and put in garbage according to regulations; Sharing bicycles is uncivilized... Last year, Shenzhen took the lead in issuing and implementing the regulations on civilized behavior of Shenzhen Special Economic Zone, and first introduced the list of uncivilized behavior control. Promote civilization by rule of law, guarantee civilization by mechanism, boost civilization by science and technology, nourish civilization by culture, jointly build and share civilization, and spread and carry forward civilization. To build a national model city of civilization, Shenzhen keeps walking. Building a benchmark for people's well-being Create a high-quality and balanced development area of national compulsory education and promote collectivized school running; 178 kindergartens and primary and secondary schools were newly renovated and expanded, and 200000 basic education degrees were added Over the past few years, Shenzhen, which has worked hard towards the goal of building a benchmark for people's well-being and is unwilling to be a "single champion", has strengthened reform and investment in education, medical care and pension, and solved the problems of education, medical care, pension, culture and ecological environment one by one, We will strive to make the people's sense of gain better, their sense of happiness more sustainable and their sense of security more secure. Facing the concerns of people's livelihood about the lack of degrees, Shenzhen plans to build four "high school parks", explore and implement the enrollment methods of "university area", build Pingshan High School Park, focus on the battle of degree construction, and promote the high-quality development of education. Focusing on the short board of medical and health care, Shenzhen issued and implemented the first local health regulations in China, issued emergency regulations for public health emergencies, launched the construction of a new system and mechanism Academy of Medical Sciences, and improved the integrated high-quality and efficient medical service system dominated by 23 regional medical centers and 20 grass-roots medical groups. Adhere to the principle of "housing without speculation". Last year, Shenzhen took the lead in establishing a reference price release mechanism for second-hand housing transactions and implemented a large-scale housing construction plan. Last year, it raised 96500 sets of public housing and supplied 42300 sets; The construction raised 117000 rental housing units and 15.28 million square meters of newly started housing. Shenzhen has also started to transform 65 old residential areas to make the life of residents in old residential areas more comfortable. The water is clear, the shore is green, the fish is flying at the shallow bottom, the water and grass are abundant, and egrets are flocking... Such an ecological environment in Shenzhen is not just imagination. Shenzhen is determined to win the battle of pollution prevention and control. At present, 159 black and smelly water bodies and 1467 small black and smelly water bodies in Shenzhen have been eliminated stably. The water quality of the assessment sections of the five major rivers has reached class IV or above, the average water quality of the national examination sections of Maozhou River and Shenzhen River has reached class IV of surface water, and the average water quality of the provincial examination sections of Guanlan River, Longgang River and Pingshan river has reached class III of surface water. Citizens' well-being and sense of access to water ecological environment have significantly improved. "Shenzhen Blue" and "thousand garden city" are the beautiful business cards of Shenzhen. The forest is in the city, and the city is in the forest. Citizens see green through the window and flowers in the four seasons. In 2021, Shenzhen PM2 5. The average annual concentration is 18 μ g / m3, the ratio of days with excellent air quality (AQI excellent ratio) is 96.2%, and the comprehensive index of ambient air quality ranks first among the mega cities in China. Bravely set the tide and demonstrate first. The construction of the leading demonstration area of socialism with Chinese characteristics has been comprehensively and deeply promoted, and Shenzhen is trying to write more "stories of spring". ■ first line cases Scientific and technological innovation of Shenzhen Bay laboratory takes an unusual road Put on the lab clothes, put on the nitrile gloves for disinfection, take out the small test tubes in the - 80 ℃ ultra-low temperature refrigerator, and put the frozen human cell lines in the test tubes in the Petri dish... "Feeder cells" is the research routine of CAI Yuxuan, a distinguished researcher of Shenzhen Bay Laboratory. His team and another research group are working together to carry out research on the regulation of protein activity related to tumor diseases. Scientists can devote themselves to climbing the peak of scientific research thanks to the system and mechanism of "taking scientists as the core" of Shenzhen Bay laboratory. Shenzhen Bay laboratory is a major innovation carrier in the field of biomedicine that fully supports the construction of Shenzhen's leading demonstration zone for the practice of socialism with Chinese characteristics. In accordance with the "four aspects", the laboratory explores and practices a new national system and new scientific research model, guided by the collaborative solution of major scientific problems in life and health, and characterized by it + Bt integration and interdisciplinary intersection, focuses on the prevention, diagnosis and treatment of major diseases such as tumor, neurodegenerative and infectious diseases, and carries out basic and original research in the fields of disease prediction, drug development, medical imaging and auxiliary diagnosis and treatment. The traditional scientific research management system has a strong administrative color. Shenzhen Bay laboratory, which has no historical burden, dares to innovate the system and mechanism