On December 23, the 20th anniversary of the establishment of Guangzhou Center for Disease Control and prevention and the public health summit forum were held in Guangzhou. Zhong Nanshan, director of the Chinese Academy of engineering, and many experts from China China Center for Disease Control and prevention, Gao Fu, have made a report on the hot topics of COVID-19's epidemic situation and the effectiveness of the new crown vaccine. Zhong Nanshan pointed out that the Omicron mutant is highly infectious, but its pathogenicity and harmfulness need to be studied. He stressed that to deal with the Omicron mutant, we should respect knowledge and experts, and minimize the impact on social production when formulating policies. The coverage of Omicron tends to expand We must be highly vigilant At present, the variant of COVID-19 has been spreading in many countries and regions around the world. Guangzhou has also reported 3 cases of imported overseas cases. At the forum, experts carried out relevant research and judgment around Omicron. Zhong Nanshan pointed out that at present, the transmission speed of Omicron mutant is very fast, and the coverage tends to expand. Of the new cases in the United States, 72% are now infected with the Omicron strain. "It took two months for the delta strain to become the mainstream strain. The Omicron strain was found in October this year. It is expected that the number of infection cases will continue to increase during this period." He stressed that we must be highly vigilant in the face of Omicron. Zhong Nanshan said that the Omicron mutant is highly infectious, but its pathogenicity and harmfulness need to be studied. He stressed that to deal with the Omicron mutant, we should respect knowledge and experts, fully consider expert opinions when formulating policies, achieve accurate tracking, scientific prevention and control, and minimize the impact on social production. Zhang zhoubin, deputy director of Guangzhou CDC, said that the timely control of traffic in Guangzhou when the Omicron case was found was a new measure to deal with this mutant strain with faster transmission speed. "We need to upgrade, carry out pre deployment, and quickly control close contact and secondary close contact sites. At present, the epidemic situation has also been better handled." He said that at present, domestic detection reagents are sensitive to Omicron, and the protection strategy is also effective. "We should have confidence". Where might the Omicron mutant come from? Goff introduced three hypotheses. The first is probably from the AIDS patients, and COVID-19 spreads back and forth between AIDS patients with low immunity. The second possibility is that COVID-19 entered the animal body in some place and then infected humans. The third is that this mutant has existed for a long time, but the original detection ability is insufficient and has not been found. Facing Omicron Vaccination booster is still effective In the face of constantly changing COVID-19, is there any protective effect of the new crown vaccine? Zhong Nanshan said that the domestic new crown vaccine is effective against delta virus, and the effective rate in preventing severe cases has reached 100%. Gao Fu pointed out that vaccination is not only to prevent infection, but also to prevent disease and transmission. "Now it seems that the protective effect of the vaccine against the mutant strain will be discounted, but it is still effective in preventing severe illness and death. Therefore, the vaccine should still be vaccinated, which can reduce the disease burden and reduce the hospitalization rate." Gao Fu also shared his latest research on the new crown vaccine. Recently, he and other experts pointed out in a paper published on the preprint website biorxiv that the Omicron mutant does have serious immune escape in the serum of rehabilitated patients, but the neutralization activity will be better preserved in the human body inoculated with three doses of inactivated vaccine or protein subunit vaccine. Zhang zhoubin said that the role of the vaccine is to build an immune barrier for the population. "From the present point of view, we should unswervingly inoculate the new crown vaccine against COVID-19, whether it is delta or Amy, or other possible variants in the future. In order to meet the need of strengthening immunization, we should strengthen immunization in time. We should complete the whole process of vaccination in time without completing the whole immunization." At present, it has entered the season of high incidence of influenza. Zhang zhoubin called on everyone to actively vaccinate influenza vaccine while vaccinating Xinguan vaccine, but pay attention to interval vaccination. "Vaccination can effectively prevent diseases, but it will not produce protection immediately after vaccination. Don't wait until the epidemic comes to think of vaccination." He stressed that in daily life, we should also take physical protective measures such as wearing masks, washing hands frequently, more ventilation and keeping social distance from gathering, so as to better deal with respiratory infectious diseases. From "SARS" to "new crown" Guangzhou's disease control capability has been continuously improved In 2001, Guangzhou CDC was officially established. Two years later, in 2003, "SARS" raided Guangdong, and the newly established Guangzhou CDC withstood a severe test. Zhong Nanshan recalled that what he most impressed at that time was the confirmation of the pathogen of SARS and the traceability of the SARS virus. "At that time, chlamydia infection was reported, but Guangdong experts thought it was viral infection and coronavirus infection. They adhered to the right direction." At that time, experts judged that the intermediate host of SARS coronavirus infection was carnivore like animal. In 2004, Guangzhou CDC released research on the SARS antibody against the antibody of the wild animal market practitioners. The paper points out that in May 2003, the antibody positive rate of wildlife practitioners was 25%, and by July 2004, the antibody positive level decreased to 5%. The prohibition of the sale of masked civet can reduce the infection rate of SARS virus, confirming the judgement of Guangdong experts before. It was with the attitude of respecting science and seeking truth from facts that Guangdong won the war of SARS. These valuable experiences novel coronavirus pneumonia have been promoted in the new crown pneumonia outbreak. Zhong Nanshan said that when Guangzhou responded to the local epidemic caused by delta strain this year, it provided a valuable reference for China's epidemic prevention and control by quickly locking the source of infection and updating the concept of "close connection". "We changed the concept of close contacts, expanded the scope of close contact, established a yellow code system, and finally controlled the epidemic in 29 days." Zhong Nanshan pointed out that Guangzhou did not seal and control the whole city, but locked specific areas of Liwan District for management, taking into account economic operation and epidemic prevention and control, "well done". The application of new technologies has also improved the ability of epidemic prevention and control. He Weiyun, Party Secretary of Guangzhou CDC, said that in recent years, the center has greatly improved the speed and efficiency of flow dispatching through the construction of information system. The background command center can record and view the flow dispatching information in front in real time for command and dispatching. "Once a positive person is found in the preliminary screening, we will send someone to do flow adjustment. When the review results come out, the flow adjustment is also completed." He Weiyun said that at present, for the new close contact and secondary close contact personnel, they will also "take a step early" to carry out detailed investigation and "run" in front of the virus. (Xinhua News Agency)