The International Science and Technology Innovation Center is an important hub of the global innovation network, not only producing disruptive innovation results and promoting industrial transformation, but also serving as a strategic high ground that affects the world's scientific and technological innovation competition pattern and an important source of new quality productivity development. It represents the maximum level that the host country can achieve in the global division of labor system. The layout and construction of international science and technology innovation centers have become important measures for major developed economies to cope with the new round of technological revolution and industrial transformation, and enhance national core competitiveness. The report of the 20th National Congress of the Communist Party of China pointed out the need to coordinate and promote the construction of international and regional science and technology innovation centers, and enhance the overall efficiency of the national innovation system. The Third Plenum of the 20th Central Committee of the Communist Party of China further proposed to promote the coordination between the central and local governments in scientific and technological innovation, and to coordinate the construction of various scientific and technological innovation platforms. What conditions are required to build a technology innovation center with global influence? Looking at the development practice of global science and technology innovation centers, it can be seen that the global leading force of original innovation, the global driving force of industrial transformation, the global gathering force of innovative talents, and the global attractiveness of the innovation environment have become essential elements for science and technology innovation centers with global influence. Leading force of original innovation. Basic research is the source of the entire scientific system, the core force that enhances a country's original innovation capability, cultivates and supports emerging interdisciplinary fields, and leads the trend of international scientific and technological innovation development. It is the "master switch" for all technological issues. After long-term efforts, China's basic research capabilities have significantly improved and it has entered the ranks of innovative countries. The three major international science and technology innovation centers in Beijing, Shanghai, and the Guangdong Hong Kong Macao Greater Bay Area have ranked among the top 10 global science and technology innovation clusters. To build a technology innovation center with global influence, it is necessary to have a group of research-oriented universities and research institutes that focus on cutting-edge technology, aiming at the forefront of world science and technology and major national strategic needs, concentrating on the layout and construction of national major science and technology infrastructure clusters, organizing the promotion of strategic oriented systematic basic research, frontier oriented exploratory basic research, market-oriented applied basic research, and striving to break through the basic theories and underlying principles behind key core technologies. Connecting the "first mile" of basic research, creating a source of original innovation, and enabling original and disruptive technological innovations to emerge one after another, becoming an important engine for promoting global innovation and development, and seizing the high ground of global science and technology. The driving force of industrial transformation. The driving ability of industrial transformation is an important symbol of science and technology innovation centers. International science and technology innovation centers in different periods of history have been gathering places for emerging technologies and industrial innovations, and have also been the leading places for world industrial transformation. They represent the most advanced productive forces of their time and play a prominent role in driving industrialization and economic growth through industry. Its typical feature is the continuous emergence of new enterprises, new industries, and new formats, and the continuous transformation and upgrading of the product structure, technological structure, and organizational structure of traditional industries. The construction of a science and technology innovation center with global influence should highlight the use of technological innovation to lead industrial innovation, solidly promote the deep integration of technological innovation and industrial innovation, and establish a full chain transformation and innovation mechanism for scientific and technological achievements from applied basic research, technological maturity, industrial incubation, enterprise docking, and achievement landing. Vigorously developing professional technical services, technology promotion, technology consulting, technology incubation, technology market, technology evaluation and other technology service industries, strengthening the dominant position of enterprises in technological innovation, actively guiding financial support for technological innovation and industrial innovation, and timely applying innovative achievements to specific industries, becoming an important source of new technologies, new products and new models worldwide and an important force leading the transformation of the global technology industry. Gathering innovative talents. Innovation driven is essentially talent driven, and innovative talents are the primary resource and core element of science and technology innovation centers. Without the gathering of innovative talents, it is impossible to lead original innovation and drive industrial transformation. All global science and technology innovation centers are talent centers without exception, and the transfer of talent centers often indicates the transformation of science and technology innovation centers. Since the 21st century, the global technological innovation landscape has gradually developed towards multipolarity, and innovation factors have become an important trend in the evolution of the international innovation pattern along with the systematic eastward shift of the economic center. The global high-end innovation factors are accelerating their agglomeration in the Asia Pacific region. The construction of a science and technology innovation center with global influence should closely focus on the core functional positioning of an innovative talent gathering place, and be committed to building a global innovation talent highland. Transforming from a single "policy talent attraction" to a multidimensional "environment talent gathering", improving the mechanism for independent talent cultivation internally, coordinating the reform of education, technology and talent integration, accelerating the construction of a national high-level talent highland and attracting talent gathering platform. Accelerate the construction of national strategic talent, focus on cultivating strategic scientists, first-class scientific and technological leaders, and innovative teams. Implement a more proactive talent introduction strategy externally, improve the support and guarantee mechanism for overseas talent introduction, attract high-end overseas talents to return, and explore the establishment of a high-tech talent immigration system. Establish a talent system that is more in line with the laws of talent growth, and gather innovative talents from home and abroad with more open policies. Attractive innovation environment. A good innovation environment is the fundamental condition and important support for the formation of science and technology innovation centers. In the era of economic globalization, innovative elements such as technology, capital, and talent break through national boundaries. Some regions attract more high-quality innovation resources through a favorable innovation environment, gradually gathering innovative talents, driving industrial transformation, leading original innovation, and becoming hubs of the global innovation network. Building a science and technology innovation center with global influence requires creating a more attractive research environment, business environment, and innovation ecosystem. Enhance the internationalization level of the entire regional innovation system, including universities, research institutes, and enterprises, and encourage various qualified institutions to participate in international large-scale scientific programs and projects. Attract global scientists, entrepreneurs, and entrepreneurs to conduct scientific research and engage in innovation and entrepreneurship. Build a cross-border technology innovation cooperation platform, promote the opening up of various technology innovation plans and projects to the outside world, actively introduce world-class technology intermediary service agencies, and promote knowledge sharing and technology transfer. Build a regulatory system that conforms to the laws of technological innovation and matches the needs of the construction of science and technology innovation centers, and strengthen intellectual property protection. Cultivate an innovative culture and create a social atmosphere that respects creativity, dares to innovate, and tolerates failure. (New Society)